Betulinic acid protects against ovarian impairment by decreasing F-2 toxin-induced oxidative stress and inflammation associated with the downregulation of p38 expression in mice

Betulinic acid protects against ovarian impairment by decreasing F-2 toxin-induced oxidative stress and inflammation associated with the downregulation of p38 expression in mice

F-2 toxin is an estrogenic mycotoxin that causes reproductive disorders in animals. Betulinic acid (BA) is a natural pentacyclic lupane-structure triterpenoid that has diverse pharmacological activities. In this study, the antioxidative and anti-inflammatory effects of BA and its underlying mechanis...

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Bibliographic Details
Main Authors: Li Kong, Xinyu Gao, Lijuan Zhu, Xing Lin, You Huang, Chunlin Huang, Wenjiang Yang, Yazhi Chen, Haoqiang Zhao, Jing Wu, Zhihang Yuan, Jin’e Yi
Format: Article
Language:English
Published: Tsinghua University Press 2024-05-01
Series:Food Science and Human Wellness
Subjects:
betulinic acid
f-2 toxin
ovarian damage
p38 mapk signaling pathway
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2022.9250108
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