Advances in liver organoids: replicating hepatic complexity for toxicity assessment and disease modeling
Abstract The lack of in vivo accurate human liver models hinders the investigation of liver-related diseases, injuries, and drug-related toxicity, posing challenges for both basic research and clinical applications. Traditional cellular and animal models, while widely used, have significant limitati...
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Main Authors: | Weidong Shao, Hui Xu, Kanghua Zeng, Mingzhou Ye, Renjun Pei, Kai Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-025-04139-2 |
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