Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy

Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy

Abstract Background The increased apoptosis of bile duct epithelial cells (BECs) due to some damage factors is considered the initiating factor in the occurrence and progression of biliary atresia (BA). Vitamin D receptor (VDR) is thought to play a crucial role in maintaining the intrinsic immune ba...

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Bibliographic Details
Main Authors: Na Liu, Pu Zhao, Ping Cao, JunPeng Hui, YongKang Pan, Jiwen Cheng
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Gastroenterology
Subjects:
Biliary atresia
Vitamin D receptor
Biliary epithelial cell
Autophagy
Double-stranded RNA virus
Online Access:https://doi.org/10.1186/s12876-025-03640-5
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