An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth

Squamous cell carcinoma is the most common head and neck malignancy. It can occur in the mandible or maxilla without a preexisting oral mucosal lesion. Often, the clinical and radiographic presentation of SCC directs the clinician to favour malignancy over other pathological conditions. However, SCC...

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Main Authors: Johnson Cheung, Ayham Al Afif, Martin Joseph Bullock, Chad Robertson, Robert Hart, Reginald Goodday
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2019/8360357
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author Johnson Cheung
Ayham Al Afif
Martin Joseph Bullock
Chad Robertson
Robert Hart
Reginald Goodday
author_facet Johnson Cheung
Ayham Al Afif
Martin Joseph Bullock
Chad Robertson
Robert Hart
Reginald Goodday
author_sort Johnson Cheung
collection DOAJ
description Squamous cell carcinoma is the most common head and neck malignancy. It can occur in the mandible or maxilla without a preexisting oral mucosal lesion. Often, the clinical and radiographic presentation of SCC directs the clinician to favour malignancy over other pathological conditions. However, SCC may also mimic an infectious condition and therefore can pose a diagnostic challenge even for the most experienced clinicians. Herein, we report a case of mandibular squamous cell carcinoma in a 53-year-old male who presented with symptoms of right facial swelling, trismus, pain, and right-sided lip paresthesia. The patient underwent a surgical removal of the presumed infected third molar of the right mandible, but histopathological analysis of the associated soft tissue unexpectedly yielded squamous cell carcinoma. Given the biopsy-proven diagnosis, the patient received a mandibular resection of the tumor followed by primary reconstruction with a fibular free flap. Patients presenting with symptoms mimicking odontogenic infections should receive vigilant attention by clinicians with regard to the disease history, clinical signs, radiographic evidence, and decision for histopathological analysis. This is especially true in the context of impacted dentition, where malignancy must be considered when formulating a differential diagnosis.
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spelling doaj-art-1337ca1fd98c42489dda7dccc62701712025-02-03T06:11:33ZengWileyCase Reports in Surgery2090-69002090-69192019-01-01201910.1155/2019/83603578360357An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom ToothJohnson Cheung0Ayham Al Afif1Martin Joseph Bullock2Chad Robertson3Robert Hart4Reginald Goodday5Department of Oral and Maxillofacial Surgery, Dalhousie University, 5981 University Avenue, Room 5132, P.O. Box 15000, Halifax, Nova Scotia, B3H 4R2, CanadaDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, QEII Health Sciences Centre 3rd floor Dickson Building, 5820 University Avenue, Halifax, Nova Scotia, B3H 1Y9, CanadaDepartment of Pathology, Dalhousie University, Sir Charles Tupper Medical Building, Room 11B, 5850 College Street, PO Box 15000, Halifax, Nova Scotia, B3H 4R2, CanadaDepartment of Oral and Maxillofacial Surgery, Dalhousie University, 5981 University Avenue, Room 5132, P.O. Box 15000, Halifax, Nova Scotia, B3H 4R2, CanadaDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, QEII Health Sciences Centre 3rd floor Dickson Building, 5820 University Avenue, Halifax, Nova Scotia, B3H 1Y9, CanadaDepartment of Oral and Maxillofacial Surgery, Dalhousie University, 5981 University Avenue, Room 5132, P.O. Box 15000, Halifax, Nova Scotia, B3H 4R2, CanadaSquamous cell carcinoma is the most common head and neck malignancy. It can occur in the mandible or maxilla without a preexisting oral mucosal lesion. Often, the clinical and radiographic presentation of SCC directs the clinician to favour malignancy over other pathological conditions. However, SCC may also mimic an infectious condition and therefore can pose a diagnostic challenge even for the most experienced clinicians. Herein, we report a case of mandibular squamous cell carcinoma in a 53-year-old male who presented with symptoms of right facial swelling, trismus, pain, and right-sided lip paresthesia. The patient underwent a surgical removal of the presumed infected third molar of the right mandible, but histopathological analysis of the associated soft tissue unexpectedly yielded squamous cell carcinoma. Given the biopsy-proven diagnosis, the patient received a mandibular resection of the tumor followed by primary reconstruction with a fibular free flap. Patients presenting with symptoms mimicking odontogenic infections should receive vigilant attention by clinicians with regard to the disease history, clinical signs, radiographic evidence, and decision for histopathological analysis. This is especially true in the context of impacted dentition, where malignancy must be considered when formulating a differential diagnosis.http://dx.doi.org/10.1155/2019/8360357
spellingShingle Johnson Cheung
Ayham Al Afif
Martin Joseph Bullock
Chad Robertson
Robert Hart
Reginald Goodday
An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
Case Reports in Surgery
title An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_full An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_fullStr An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_full_unstemmed An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_short An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth
title_sort unusual case of mandibular squamous cell carcinoma in intimacy with an impacted wisdom tooth
url http://dx.doi.org/10.1155/2019/8360357
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