miR-139-5p activates ferroptosis by inhibiting the expression of HMG-CoA reductase to inhibit the progression of glioma

Abstract Glioma is the most aggressive and common tumour in the central nervous system. It has been reported that miR-139-5p plays an important role in regulating tumour progression. However, whether miR-139-5p affects the progression of glioma and the specific mechanism remains to be explored. Thro...

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Bibliographic Details
Main Authors: Zhongsheng You, Fei Wu, Yaofeng Zheng, Hongling Yang, Jianbo Ye, Hongyi Cai, Chuangcai Luo, Yang Liu, Yiquan Ke, Xiangdong Xu
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02532-7
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