Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1

Abstract Salt stress poses a severe threat to global rice productivity, and developing salt-tolerant cultivars represents a critical strategy to address this challenge. However, the molecular mechanisms underlying salt tolerance in rice remain elusive. This study focuses on NGY1, a crossbred offspri...

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Main Authors: Cheng Li, Kai Lu, Wen-Hua Liang, Tao Chen, Shu Yao, Lei He, Xiao-Dong Wei, Ling Zhao, Li-Hui Zhou, Chun-Fang Zhao, Qing-Yong Zhao, Zhen Zhu, Cai-Lin Wang, Ya-Dong Zhang
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:Rice
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Online Access:https://doi.org/10.1186/s12284-025-00802-7
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author Cheng Li
Kai Lu
Wen-Hua Liang
Tao Chen
Shu Yao
Lei He
Xiao-Dong Wei
Ling Zhao
Li-Hui Zhou
Chun-Fang Zhao
Qing-Yong Zhao
Zhen Zhu
Cai-Lin Wang
Ya-Dong Zhang
author_facet Cheng Li
Kai Lu
Wen-Hua Liang
Tao Chen
Shu Yao
Lei He
Xiao-Dong Wei
Ling Zhao
Li-Hui Zhou
Chun-Fang Zhao
Qing-Yong Zhao
Zhen Zhu
Cai-Lin Wang
Ya-Dong Zhang
author_sort Cheng Li
collection DOAJ
description Abstract Salt stress poses a severe threat to global rice productivity, and developing salt-tolerant cultivars represents a critical strategy to address this challenge. However, the molecular mechanisms underlying salt tolerance in rice remain elusive. This study focuses on NGY1, a crossbred offspring between YF47 and SN9903, which showed superior salt tolerance compared to its parent lines during the seedling stage. RNA sequencing (RNA-seq) of seedlings harvested at distinct temporal stages of salt stress identified over 10,000 differentially expressed genes (DEGs). Functional enrichment analyses (GO and KEGG) revealed that NGY1 uniquely mobilized a broader repertoire of stress-responsive genes within shorter timeframes than its parents lines, particularly those associated with redox homeostasis, phytohormone signaling, and MAPK cascades. Meanwhile, NGY1 can rapidly upregulate genes related to salt tolerance compared to its parent during the initial stress phase. Additionally, differences in salt tolerance between NGY1 and its parents were linked to variations in alternative splicing and the high expression of certain NBS-LRR protein genes early in salt stress exposure. These findings not only provide new insights into the molecular mechanisms of salt tolerance, but also provide a theoretical basis for genetic improvement of salt tolerance in rice.
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spelling doaj-art-13092f9a23f848d2ba62ad9d0f20c8a52025-08-20T02:31:09ZengSpringerOpenRice1939-84251939-84332025-06-0118111310.1186/s12284-025-00802-7Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1Cheng Li0Kai Lu1Wen-Hua Liang2Tao Chen3Shu Yao4Lei He5Xiao-Dong Wei6Ling Zhao7Li-Hui Zhou8Chun-Fang Zhao9Qing-Yong Zhao10Zhen Zhu11Cai-Lin Wang12Ya-Dong Zhang13Institute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceInstitute of Food Crops/Nanjing Branch of China National Center for Rice Improvement/National Center of Technology Innovation for Saline-Alkali Tolerant Rice/Zhongshan Biological Breeding Laboratory/Jiangsu Academy of Agricultural ScienceAbstract Salt stress poses a severe threat to global rice productivity, and developing salt-tolerant cultivars represents a critical strategy to address this challenge. However, the molecular mechanisms underlying salt tolerance in rice remain elusive. This study focuses on NGY1, a crossbred offspring between YF47 and SN9903, which showed superior salt tolerance compared to its parent lines during the seedling stage. RNA sequencing (RNA-seq) of seedlings harvested at distinct temporal stages of salt stress identified over 10,000 differentially expressed genes (DEGs). Functional enrichment analyses (GO and KEGG) revealed that NGY1 uniquely mobilized a broader repertoire of stress-responsive genes within shorter timeframes than its parents lines, particularly those associated with redox homeostasis, phytohormone signaling, and MAPK cascades. Meanwhile, NGY1 can rapidly upregulate genes related to salt tolerance compared to its parent during the initial stress phase. Additionally, differences in salt tolerance between NGY1 and its parents were linked to variations in alternative splicing and the high expression of certain NBS-LRR protein genes early in salt stress exposure. These findings not only provide new insights into the molecular mechanisms of salt tolerance, but also provide a theoretical basis for genetic improvement of salt tolerance in rice.https://doi.org/10.1186/s12284-025-00802-7RiceSalt-stressTranscriptomicAlternative splicingMechanism
spellingShingle Cheng Li
Kai Lu
Wen-Hua Liang
Tao Chen
Shu Yao
Lei He
Xiao-Dong Wei
Ling Zhao
Li-Hui Zhou
Chun-Fang Zhao
Qing-Yong Zhao
Zhen Zhu
Cai-Lin Wang
Ya-Dong Zhang
Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1
Rice
Rice
Salt-stress
Transcriptomic
Alternative splicing
Mechanism
title Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1
title_full Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1
title_fullStr Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1
title_full_unstemmed Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1
title_short Transcriptome Analysis Between Parents and Offspring Revealed the Early Salt Tolerance Mechanism of Rice NGY1
title_sort transcriptome analysis between parents and offspring revealed the early salt tolerance mechanism of rice ngy1
topic Rice
Salt-stress
Transcriptomic
Alternative splicing
Mechanism
url https://doi.org/10.1186/s12284-025-00802-7
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