Preparation of curcumin submicron particles by supercritical antisolvent method with external adjustable annular gap nozzle

Abstract The supercritical antisolvent (SAS) method can effectively improve the bioavailability of poorly water-soluble drugs. However, the current supercritical equipment and processes were not fully developed, making industrialization difficult to achieve. Therefore, an externally adjustable annul...

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Bibliographic Details
Main Authors: Yechen Wang, Zirui Li, Sun Fayu, Fei Li, Weiqiang Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-87787-x
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