Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.

<h4>Background</h4>Pterygium is a common chronic ophthalmic condition, which may result in significant visual morbidity or lead to blindness in extreme cases. The prevalence of pterygium in China has not been reported at the sub-national level.<h4>Methods</h4>In this study, w...

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Main Authors: Peige Song, Xinlei Chang, Manli Wang, Lin An
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0174587
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author Peige Song
Xinlei Chang
Manli Wang
Lin An
author_facet Peige Song
Xinlei Chang
Manli Wang
Lin An
author_sort Peige Song
collection DOAJ
description <h4>Background</h4>Pterygium is a common chronic ophthalmic condition, which may result in significant visual morbidity or lead to blindness in extreme cases. The prevalence of pterygium in China has not been reported at the sub-national level.<h4>Methods</h4>In this study, we conducted a systematic review and meta-analysis to estimate the prevalence of pterygium in China. China National Knowledge Infrastructure (CNKI), Wanfang, Chinese Biomedicine Literature Database (CBM-SinoMed), PubMed, Embase and Medline were searched before September 2016. We performed a multilevel mixed-effect meta-regression based on the included studies, our results showed that age, gender and latitude were significantly associated with pterygium prevalence. Based on the final model, the age and gender-specific prevalence of pterygium in 31 Chinese provinces (except Hongkong, Macau and Taiwan) and the whole country was generated.<h4>Results</h4>In 2010, the overall prevalence of pterygium in Chinese people aged 15-84 years was 9.84% (95% CI: 6.72-14.14), and the number of pterygium cases in China was 108.65 million (95% CI: 74.23-156.13).<h4>Conclusions</h4>In conclusion, the prevalence of pterygium in Chinese population in 2010 was estimated at both the national and provincial levels. The higher burden of pterygium across the country calls for efforts to advocate public health education encouraging people to take appropriate protective measures.
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spelling doaj-art-12ec8a669b3f4e7b8db1e4cf51e48fc92025-08-20T03:32:15ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01123e017458710.1371/journal.pone.0174587Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.Peige SongXinlei ChangManli WangLin An<h4>Background</h4>Pterygium is a common chronic ophthalmic condition, which may result in significant visual morbidity or lead to blindness in extreme cases. The prevalence of pterygium in China has not been reported at the sub-national level.<h4>Methods</h4>In this study, we conducted a systematic review and meta-analysis to estimate the prevalence of pterygium in China. China National Knowledge Infrastructure (CNKI), Wanfang, Chinese Biomedicine Literature Database (CBM-SinoMed), PubMed, Embase and Medline were searched before September 2016. We performed a multilevel mixed-effect meta-regression based on the included studies, our results showed that age, gender and latitude were significantly associated with pterygium prevalence. Based on the final model, the age and gender-specific prevalence of pterygium in 31 Chinese provinces (except Hongkong, Macau and Taiwan) and the whole country was generated.<h4>Results</h4>In 2010, the overall prevalence of pterygium in Chinese people aged 15-84 years was 9.84% (95% CI: 6.72-14.14), and the number of pterygium cases in China was 108.65 million (95% CI: 74.23-156.13).<h4>Conclusions</h4>In conclusion, the prevalence of pterygium in Chinese population in 2010 was estimated at both the national and provincial levels. The higher burden of pterygium across the country calls for efforts to advocate public health education encouraging people to take appropriate protective measures.https://doi.org/10.1371/journal.pone.0174587
spellingShingle Peige Song
Xinlei Chang
Manli Wang
Lin An
Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.
PLoS ONE
title Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.
title_full Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.
title_fullStr Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.
title_full_unstemmed Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.
title_short Variations of pterygium prevalence by age, gender and geographic characteristics in China: A systematic review and meta-analysis.
title_sort variations of pterygium prevalence by age gender and geographic characteristics in china a systematic review and meta analysis
url https://doi.org/10.1371/journal.pone.0174587
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AT xinleichang variationsofpterygiumprevalencebyagegenderandgeographiccharacteristicsinchinaasystematicreviewandmetaanalysis
AT manliwang variationsofpterygiumprevalencebyagegenderandgeographiccharacteristicsinchinaasystematicreviewandmetaanalysis
AT linan variationsofpterygiumprevalencebyagegenderandgeographiccharacteristicsinchinaasystematicreviewandmetaanalysis