ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES
Several organotin(IV) derivatives of phenolic Schiff bases were prepared and investigated by spectroscopic methods. These compounds were bioassayed to evaluate their bacterial effect against Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Salmonel...
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| Format: | Article |
| Language: | English |
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Universidade Federal de Viçosa (UFV)
2019-12-01
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| Series: | The Journal of Engineering and Exact Sciences |
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| Online Access: | https://periodicos.ufv.br/jcec/article/view/8884 |
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| author | Ane Francielly da Silva Santos José Roberto da Silveira Maia |
| author_facet | Ane Francielly da Silva Santos José Roberto da Silveira Maia |
| author_sort | Ane Francielly da Silva Santos |
| collection | DOAJ |
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Several organotin(IV) derivatives of phenolic Schiff bases were prepared and investigated by spectroscopic methods. These compounds were bioassayed to evaluate their bacterial effect against Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Salmonella typhimurium) microorganisms. Dimeric and monomeric compounds were characterized by infrared in solid state. Metallic centers having penta-, hexa-, and heptacoordination were identified by multinuclear NMR (1H, 13C and 119Sn) in solution. The di- and triorganotin(IV) derivatives were also investigated by conductimetric measurements in methanol, elemental analysis and melting point. The bioassay of these tin(IV) compounds showed that the best resulting activity was against S. aureus for the triphenyltin(IV) phenolic Schiff base derivatives, presenting MICs of 1.1 µM (0.6 mg mL-1) and 2.2 µM (1.3 mg mL-1).
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| format | Article |
| id | doaj-art-12e2fc421cce4e3db4cae948e9e58c8a |
| institution | Kabale University |
| issn | 2527-1075 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Universidade Federal de Viçosa (UFV) |
| record_format | Article |
| series | The Journal of Engineering and Exact Sciences |
| spelling | doaj-art-12e2fc421cce4e3db4cae948e9e58c8a2025-02-02T19:58:36ZengUniversidade Federal de Viçosa (UFV)The Journal of Engineering and Exact Sciences2527-10752019-12-015510.18540/jcecvl5iss5pp0452-0459ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASESAne Francielly da Silva Santos0José Roberto da Silveira Maia1Federal Institute of Mato GrossoUniversidade federal de Viçosa Several organotin(IV) derivatives of phenolic Schiff bases were prepared and investigated by spectroscopic methods. These compounds were bioassayed to evaluate their bacterial effect against Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Salmonella typhimurium) microorganisms. Dimeric and monomeric compounds were characterized by infrared in solid state. Metallic centers having penta-, hexa-, and heptacoordination were identified by multinuclear NMR (1H, 13C and 119Sn) in solution. The di- and triorganotin(IV) derivatives were also investigated by conductimetric measurements in methanol, elemental analysis and melting point. The bioassay of these tin(IV) compounds showed that the best resulting activity was against S. aureus for the triphenyltin(IV) phenolic Schiff base derivatives, presenting MICs of 1.1 µM (0.6 mg mL-1) and 2.2 µM (1.3 mg mL-1). https://periodicos.ufv.br/jcec/article/view/8884Organotin(IV) compoundsCharacterizationAntimicrobial effectBactericide |
| spellingShingle | Ane Francielly da Silva Santos José Roberto da Silveira Maia ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES The Journal of Engineering and Exact Sciences Organotin(IV) compounds Characterization Antimicrobial effect Bactericide |
| title | ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES |
| title_full | ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES |
| title_fullStr | ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES |
| title_full_unstemmed | ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES |
| title_short | ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES |
| title_sort | antimicrobial effect of organotin compounds derived from phenolic schiff bases |
| topic | Organotin(IV) compounds Characterization Antimicrobial effect Bactericide |
| url | https://periodicos.ufv.br/jcec/article/view/8884 |
| work_keys_str_mv | AT anefranciellydasilvasantos antimicrobialeffectoforganotincompoundsderivedfromphenolicschiffbases AT joserobertodasilveiramaia antimicrobialeffectoforganotincompoundsderivedfromphenolicschiffbases |