Breakdown in the Organ Donation Process and Its Effect on Organ Availability
Background. This study examines the effect of breakdown in the organ donation process on the availability of transplantable organs. A process breakdown is defined as a deviation from the organ donation protocol that may jeopardize organ recovery. Methods. A retrospective analysis of donation-eligibl...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2015/831501 |
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| author | Manik Razdan Howard B. Degenholtz Jeremy M. Kahn Julia Driessen |
| author_facet | Manik Razdan Howard B. Degenholtz Jeremy M. Kahn Julia Driessen |
| author_sort | Manik Razdan |
| collection | DOAJ |
| description | Background. This study examines the effect of breakdown in the organ donation process on the availability of transplantable organs. A process breakdown is defined as a deviation from the organ donation protocol that may jeopardize organ recovery. Methods. A retrospective analysis of donation-eligible decedents was conducted using data from an independent organ procurement organization. Adjusted effect of process breakdown on organs transplanted from an eligible decedent was examined using multivariable zero-inflated Poisson regression. Results. An eligible decedent is four times more likely to become an organ donor when there is no process breakdown (adjusted OR: 4.01; 95% CI: 1.6838, 9.6414; P<0.01) even after controlling for the decedent’s age, gender, race, and whether or not a decedent had joined the state donor registry. However once the eligible decedent becomes a donor, whether or not there was a process breakdown does not affect the number of transplantable organs yielded. Overall, for every process breakdown occurring in the care of an eligible decedent, one less organ is available for transplant. Decedent’s age is a strong predictor of likelihood of donation and the number of organs transplanted from a donor. Conclusion. Eliminating breakdowns in the donation process can potentially increase the number of organs available for transplant but some organs will still be lost. |
| format | Article |
| id | doaj-art-12dbcfebaaf44950a650f787a88d7694 |
| institution | Kabale University |
| issn | 2090-0007 2090-0015 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Transplantation |
| spelling | doaj-art-12dbcfebaaf44950a650f787a88d76942025-02-03T05:59:27ZengWileyJournal of Transplantation2090-00072090-00152015-01-01201510.1155/2015/831501831501Breakdown in the Organ Donation Process and Its Effect on Organ AvailabilityManik Razdan0Howard B. Degenholtz1Jeremy M. Kahn2Julia Driessen3Health Policy and Management, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, A724B, Pittsburgh, PA 15261, USAHealth Policy and Management, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, A616, Pittsburgh, PA 15261, USACritical Care, Medicine and Health Policy, University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA 15261, USAHealth Policy and Management, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, Pittsburgh, PA 15261, USABackground. This study examines the effect of breakdown in the organ donation process on the availability of transplantable organs. A process breakdown is defined as a deviation from the organ donation protocol that may jeopardize organ recovery. Methods. A retrospective analysis of donation-eligible decedents was conducted using data from an independent organ procurement organization. Adjusted effect of process breakdown on organs transplanted from an eligible decedent was examined using multivariable zero-inflated Poisson regression. Results. An eligible decedent is four times more likely to become an organ donor when there is no process breakdown (adjusted OR: 4.01; 95% CI: 1.6838, 9.6414; P<0.01) even after controlling for the decedent’s age, gender, race, and whether or not a decedent had joined the state donor registry. However once the eligible decedent becomes a donor, whether or not there was a process breakdown does not affect the number of transplantable organs yielded. Overall, for every process breakdown occurring in the care of an eligible decedent, one less organ is available for transplant. Decedent’s age is a strong predictor of likelihood of donation and the number of organs transplanted from a donor. Conclusion. Eliminating breakdowns in the donation process can potentially increase the number of organs available for transplant but some organs will still be lost.http://dx.doi.org/10.1155/2015/831501 |
| spellingShingle | Manik Razdan Howard B. Degenholtz Jeremy M. Kahn Julia Driessen Breakdown in the Organ Donation Process and Its Effect on Organ Availability Journal of Transplantation |
| title | Breakdown in the Organ Donation Process and Its Effect on Organ Availability |
| title_full | Breakdown in the Organ Donation Process and Its Effect on Organ Availability |
| title_fullStr | Breakdown in the Organ Donation Process and Its Effect on Organ Availability |
| title_full_unstemmed | Breakdown in the Organ Donation Process and Its Effect on Organ Availability |
| title_short | Breakdown in the Organ Donation Process and Its Effect on Organ Availability |
| title_sort | breakdown in the organ donation process and its effect on organ availability |
| url | http://dx.doi.org/10.1155/2015/831501 |
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