Upper Gastrointestinal Tract Crohn's Disease
Crohn's disease may involve any site within the gastrointestinal tract. Usually pathology is present in the ileum and/or colon, but atypical presentations may occur with apparently 'isolated' involvement of the oropharynx, esophagus or gastroduodenum. If changes typical of Crohn'...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1990-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1990/758048 |
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| Summary: | Crohn's disease may involve any site within the gastrointestinal
tract. Usually pathology is present in the ileum and/or colon, but atypical presentations
may occur with apparently 'isolated' involvement of the oropharynx, esophagus
or gastroduodenum. If changes typical of Crohn's disease are detected in the
upper gastrointestinal tract, then a careful assessment is required involving
radiographic, endoscopic and histologic studies to determine if pathology is present
in more distal intestine. In addition , microbiologic studies may be important to
exclude infectious causes, especially of granulomas. If these studies are negative,
prolonged follow-up may be required to establish a diagnosis of Crohn's disease.
Although upper gastrointestinal involvement is increasingly recognized as a significant
cause of morbidity in Crohn's disease, the treatment options are limited ,
largely anecdotal and need to be the subject of detailed epidemiologic investigation
and clinical trials. |
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| ISSN: | 0835-7900 |