Mediterranean Diet and Metabolic Syndrome

Metabolic syndrome (MetS) is a major health issue defined by central obesity and at least two more of the following factors: high triglycerides, low high-density lipoprotein (HDL) cholesterol, high blood pressure, and high fasting glucose. Managing MetS involves lifestyle changes, with the adherence...

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Main Authors: Josipa Radić, Marijana Vučković, Andrej Belančić, Hana Đogaš, Mislav Radić
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Diabetology
Subjects:
Online Access:https://www.mdpi.com/2673-4540/6/1/4
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author Josipa Radić
Marijana Vučković
Andrej Belančić
Hana Đogaš
Mislav Radić
author_facet Josipa Radić
Marijana Vučković
Andrej Belančić
Hana Đogaš
Mislav Radić
author_sort Josipa Radić
collection DOAJ
description Metabolic syndrome (MetS) is a major health issue defined by central obesity and at least two more of the following factors: high triglycerides, low high-density lipoprotein (HDL) cholesterol, high blood pressure, and high fasting glucose. Managing MetS involves lifestyle changes, with the adherence to a Mediterranean diet (MeDi) playing a crucial role. MeDi, emphasizing the consumption of whole grains, fruits, vegetables, legumes, nuts, and olive oil, has been linked to a reduced risk of type 2 diabetes and improved glucoregulation. A randomized controlled trial showed that a low-carb MeDi resulted in a 30% lower relative risk of developing type 2 diabetes compared to a low-fat diet. Additionally, meta-analytic data highlighted a strong inverse relationship between adherence to the MeDi and the incidence of diabetes. Furthermore, the MeDi’s anti-inflammatory properties help manage obesity-related low-grade chronic inflammation, crucial for weight management and the improvement of quality of life. The improvement of lipid profiles, reductions in low-density lipoprotein and total cholesterol, and an increase in HDL cholesterol were also found to be linked to MeDi adherence. However, despite its benefits, adherence to the MeDi varies widely, often being low to moderate in many Mediterranean populations. Improving adherence through physician advice and patient education is crucial for maximizing the MeDi’s potential to prevent and manage diabetes and diabetes-related complications.
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spelling doaj-art-12c80475eb08431e80c58ad57b90fbb22025-01-24T13:28:45ZengMDPI AGDiabetology2673-45402025-01-0161410.3390/diabetology6010004Mediterranean Diet and Metabolic SyndromeJosipa Radić0Marijana Vučković1Andrej Belančić2Hana Đogaš3Mislav Radić4Department of Internal Medicine, Division of Nephrology and Dialysis, University Hospital of Split, 21000 Split, CroatiaDepartment of Internal Medicine, Division of Nephrology and Dialysis, University Hospital of Split, 21000 Split, CroatiaDepartment of Basic and Clinical Pharmacology with Toxicology, Faculty of Medicine, University of Rijeka, Braće Branchetta 20, 51000 Rijeka, CroatiaDepartment of Internal Medicine, Division of Nephrology and Dialysis, University Hospital of Split, 21000 Split, CroatiaInternal Medicine Department, School of Medicine, University of Split, 21000 Split, CroatiaMetabolic syndrome (MetS) is a major health issue defined by central obesity and at least two more of the following factors: high triglycerides, low high-density lipoprotein (HDL) cholesterol, high blood pressure, and high fasting glucose. Managing MetS involves lifestyle changes, with the adherence to a Mediterranean diet (MeDi) playing a crucial role. MeDi, emphasizing the consumption of whole grains, fruits, vegetables, legumes, nuts, and olive oil, has been linked to a reduced risk of type 2 diabetes and improved glucoregulation. A randomized controlled trial showed that a low-carb MeDi resulted in a 30% lower relative risk of developing type 2 diabetes compared to a low-fat diet. Additionally, meta-analytic data highlighted a strong inverse relationship between adherence to the MeDi and the incidence of diabetes. Furthermore, the MeDi’s anti-inflammatory properties help manage obesity-related low-grade chronic inflammation, crucial for weight management and the improvement of quality of life. The improvement of lipid profiles, reductions in low-density lipoprotein and total cholesterol, and an increase in HDL cholesterol were also found to be linked to MeDi adherence. However, despite its benefits, adherence to the MeDi varies widely, often being low to moderate in many Mediterranean populations. Improving adherence through physician advice and patient education is crucial for maximizing the MeDi’s potential to prevent and manage diabetes and diabetes-related complications.https://www.mdpi.com/2673-4540/6/1/4mediterranean dietmetabolic syndromediabetesarterial hypertensiondyslipidemia
spellingShingle Josipa Radić
Marijana Vučković
Andrej Belančić
Hana Đogaš
Mislav Radić
Mediterranean Diet and Metabolic Syndrome
Diabetology
mediterranean diet
metabolic syndrome
diabetes
arterial hypertension
dyslipidemia
title Mediterranean Diet and Metabolic Syndrome
title_full Mediterranean Diet and Metabolic Syndrome
title_fullStr Mediterranean Diet and Metabolic Syndrome
title_full_unstemmed Mediterranean Diet and Metabolic Syndrome
title_short Mediterranean Diet and Metabolic Syndrome
title_sort mediterranean diet and metabolic syndrome
topic mediterranean diet
metabolic syndrome
diabetes
arterial hypertension
dyslipidemia
url https://www.mdpi.com/2673-4540/6/1/4
work_keys_str_mv AT josiparadic mediterraneandietandmetabolicsyndrome
AT marijanavuckovic mediterraneandietandmetabolicsyndrome
AT andrejbelancic mediterraneandietandmetabolicsyndrome
AT hanađogas mediterraneandietandmetabolicsyndrome
AT mislavradic mediterraneandietandmetabolicsyndrome