Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women
A secondary analysis of cross-sectional data was analyzed from 6 cohorts (Fall 1995–Fall 1997) of postmenopausal women (n=266; 56.6±4.7 years) participating in the Bone Estrogen Strength Training (BEST) study (a 12-month, block-randomized, clinical trial). Bone mineral density (BMD) was measured at...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Osteoporosis |
| Online Access: | http://dx.doi.org/10.1155/2015/737521 |
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| author | Margaret Harris Vanessa Farrell Linda Houtkooper Scott Going Timothy Lohman |
| author_facet | Margaret Harris Vanessa Farrell Linda Houtkooper Scott Going Timothy Lohman |
| author_sort | Margaret Harris |
| collection | DOAJ |
| description | A secondary analysis of cross-sectional data was analyzed from 6 cohorts (Fall 1995–Fall 1997) of postmenopausal women (n=266; 56.6±4.7 years) participating in the Bone Estrogen Strength Training (BEST) study (a 12-month, block-randomized, clinical trial). Bone mineral density (BMD) was measured at femur neck and trochanter, lumbar spine (L2–L4), and total body BMD using dual-energy X-ray absorptiometry (DXA). Mean dietary polyunsaturated fatty acids (PUFAs) intakes were assessed using 8 days of diet records. Multiple linear regression was used to examine associations between dietary PUFAs and BMD. Covariates included in the models were total energy intake, body weight at year 1, years after menopause, exercise, use of hormone therapy (HT), total calcium, and total iron intakes. In the total sample, lumbar spine and total body BMD had significant negative associations with dietary PUFA intake at P<0.05. In the non-HT group, no significant associations between dietary PUFA intake and BMD were seen. In the HT group, significant inverse associations with dietary PUFA intake were seen in the spine, total body, and Ward’s triangle BMD, suggesting that HT may influence PUFA associations with BMD. This study is registered with clinicaltrials.gov, identifier: NCT00000399. |
| format | Article |
| id | doaj-art-12c1159e646346d0bdf5764f52f3627d |
| institution | Kabale University |
| issn | 2090-8059 2042-0064 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Osteoporosis |
| spelling | doaj-art-12c1159e646346d0bdf5764f52f3627d2025-02-03T01:07:14ZengWileyJournal of Osteoporosis2090-80592042-00642015-01-01201510.1155/2015/737521737521Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal WomenMargaret Harris0Vanessa Farrell1Linda Houtkooper2Scott Going3Timothy Lohman4Department of Health Sciences, University of Colorado Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USADepartment of Nutritional Sciences, University of Arizona, 1177 E. 4th Street, Tucson, AZ 85721, USANutritional Sciences Department, College of Agriculture and Life Sciences, University of Arizona, Tucson, AZ 85721-0036, USADepartment of Nutritional Sciences, University of Arizona, 1177 E. 4th Street, Tucson, AZ 85721, USADepartment of Physiology, 3017 N. Gaia Place, Tucson, AZ 85745, USAA secondary analysis of cross-sectional data was analyzed from 6 cohorts (Fall 1995–Fall 1997) of postmenopausal women (n=266; 56.6±4.7 years) participating in the Bone Estrogen Strength Training (BEST) study (a 12-month, block-randomized, clinical trial). Bone mineral density (BMD) was measured at femur neck and trochanter, lumbar spine (L2–L4), and total body BMD using dual-energy X-ray absorptiometry (DXA). Mean dietary polyunsaturated fatty acids (PUFAs) intakes were assessed using 8 days of diet records. Multiple linear regression was used to examine associations between dietary PUFAs and BMD. Covariates included in the models were total energy intake, body weight at year 1, years after menopause, exercise, use of hormone therapy (HT), total calcium, and total iron intakes. In the total sample, lumbar spine and total body BMD had significant negative associations with dietary PUFA intake at P<0.05. In the non-HT group, no significant associations between dietary PUFA intake and BMD were seen. In the HT group, significant inverse associations with dietary PUFA intake were seen in the spine, total body, and Ward’s triangle BMD, suggesting that HT may influence PUFA associations with BMD. This study is registered with clinicaltrials.gov, identifier: NCT00000399.http://dx.doi.org/10.1155/2015/737521 |
| spellingShingle | Margaret Harris Vanessa Farrell Linda Houtkooper Scott Going Timothy Lohman Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women Journal of Osteoporosis |
| title | Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women |
| title_full | Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women |
| title_fullStr | Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women |
| title_full_unstemmed | Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women |
| title_short | Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women |
| title_sort | associations of polyunsaturated fatty acid intake with bone mineral density in postmenopausal women |
| url | http://dx.doi.org/10.1155/2015/737521 |
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