Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method
The goal of this study was to fabricate Antheraea pernyi silk fibroin (ASF) microparticles using electrospinning under mild processing conditions. To improve processability of the ASF solution, poly(ethylene oxide) (PEO) was used to regulate viscosity of ASF solution for electrospinning. It was foun...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2016/8205984 |
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| author | Xiufang Li Qiang Zhang Yanfei Feng Shuqin Yan Jing Qu Renchuan You |
| author_facet | Xiufang Li Qiang Zhang Yanfei Feng Shuqin Yan Jing Qu Renchuan You |
| author_sort | Xiufang Li |
| collection | DOAJ |
| description | The goal of this study was to fabricate Antheraea pernyi silk fibroin (ASF) microparticles using electrospinning under mild processing conditions. To improve processability of the ASF solution, poly(ethylene oxide) (PEO) was used to regulate viscosity of ASF solution for electrospinning. It was found that the blend of ASF with PEO could form a bead-on-string structure with well spherical particles. Furthermore, aqueous ethanol and ultrasonic treatments could disrupt the nanofibrillar string structure between particles and ultimately produced water-insoluble ASF particles with submicron scale. Cell viability studies indicated that the ASF microparticles were nontoxic to EA926 cells. Moreover, fluorescent images based on FITC labeling showed that the ASF microparticles were easily uptaken by the cells. Aqueous-based electrospinning provides a potentially useful option for the fabrication of ASF microparticles based on this unique fibrous protein. |
| format | Article |
| id | doaj-art-129cc7cb29df466f84825f8af6caf31d |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-129cc7cb29df466f84825f8af6caf31d2025-02-03T01:31:57ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422016-01-01201610.1155/2016/82059848205984Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning MethodXiufang Li0Qiang Zhang1Yanfei Feng2Shuqin Yan3Jing Qu4Renchuan You5College of Textile Science and Engineering, Wuhan Textile University, Wuhan 430200, ChinaCollege of Textile Science and Engineering, Wuhan Textile University, Wuhan 430200, ChinaCollege of Textile Science and Engineering, Wuhan Textile University, Wuhan 430200, ChinaCollege of Textile Science and Engineering, Wuhan Textile University, Wuhan 430200, ChinaNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, ChinaCollege of Textile Science and Engineering, Wuhan Textile University, Wuhan 430200, ChinaThe goal of this study was to fabricate Antheraea pernyi silk fibroin (ASF) microparticles using electrospinning under mild processing conditions. To improve processability of the ASF solution, poly(ethylene oxide) (PEO) was used to regulate viscosity of ASF solution for electrospinning. It was found that the blend of ASF with PEO could form a bead-on-string structure with well spherical particles. Furthermore, aqueous ethanol and ultrasonic treatments could disrupt the nanofibrillar string structure between particles and ultimately produced water-insoluble ASF particles with submicron scale. Cell viability studies indicated that the ASF microparticles were nontoxic to EA926 cells. Moreover, fluorescent images based on FITC labeling showed that the ASF microparticles were easily uptaken by the cells. Aqueous-based electrospinning provides a potentially useful option for the fabrication of ASF microparticles based on this unique fibrous protein.http://dx.doi.org/10.1155/2016/8205984 |
| spellingShingle | Xiufang Li Qiang Zhang Yanfei Feng Shuqin Yan Jing Qu Renchuan You Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method Advances in Materials Science and Engineering |
| title | Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method |
| title_full | Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method |
| title_fullStr | Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method |
| title_full_unstemmed | Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method |
| title_short | Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method |
| title_sort | preparation of antheraea pernyi silk fibroin microparticles through a facile electrospinning method |
| url | http://dx.doi.org/10.1155/2016/8205984 |
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