RMDNet: RNA-aware dung beetle optimization-based multi-branch integration network for RNA–protein binding sites prediction

RMDNet: RNA-aware dung beetle optimization-based multi-branch integration network for RNA–protein binding sites prediction

Abstract RNA-binding proteins (RBPs) play crucial roles in gene regulation. Their dysregulation has been increasingly linked to neurodegenerative diseases, liver cancer, and lung cancer. Although experimental methods like CLIP-seq accurately identify RNA–protein binding sites, they are time-consumin...

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Bibliographic Details
Main Authors: Jiangbo Zhang, Yunhui Peng, Feifei Cui, Zilong Zhang, Shankai Yan, Qingchen Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Bioinformatics
Subjects:
Multi-branch deep learning network
Dung beetle optimizer
Feature fusion strategy
RNA–protein binding sites
Convolutional neural network
Graph neural network
Online Access:https://doi.org/10.1186/s12859-025-06197-y
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https://doi.org/10.1186/s12859-025-06197-y

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