Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis
Cryptococcosis usually occurs in immunocompromised patients and can cause enlargement of the adrenal glands, although the morphologic changes after treatment have not been reported in detail. We report the case of 24-year-old man with fevers, headaches, and impaired consciousness who had been treate...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2017/1543149 |
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| author | Yuka Muraoka Shintaro Iwama Hiroshi Arima |
| author_facet | Yuka Muraoka Shintaro Iwama Hiroshi Arima |
| author_sort | Yuka Muraoka |
| collection | DOAJ |
| description | Cryptococcosis usually occurs in immunocompromised patients and can cause enlargement of the adrenal glands, although the morphologic changes after treatment have not been reported in detail. We report the case of 24-year-old man with fevers, headaches, and impaired consciousness who had been treated with glucocorticoids for a protein-losing gastroenteropathy. The cerebrospinal fluid analysis revealed cryptococcal meningitis. Computed tomography showed bilateral adrenal enlargement. A retrospective analysis revealed that the enlargement had been detected 5 months before admission and gradually increased. The enlargement was improved with antifungal therapy and normalized 6 months later. This is the first report describing morphological changes in the adrenal glands associated with cryptococcal meningitis. Adrenal enlargement by cryptococcosis can be improved without any abnormal findings, including calcifications, which may be a unique characteristic from other diseases, including tuberculosis. |
| format | Article |
| id | doaj-art-12929cb19d414fb0981123b934387924 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-12929cb19d414fb0981123b9343879242025-02-03T01:07:50ZengWileyCase Reports in Endocrinology2090-65012090-651X2017-01-01201710.1155/2017/15431491543149Normalization of Bilateral Adrenal Gland Enlargement after Treatment for CryptococcosisYuka Muraoka0Shintaro Iwama1Hiroshi Arima2Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanCryptococcosis usually occurs in immunocompromised patients and can cause enlargement of the adrenal glands, although the morphologic changes after treatment have not been reported in detail. We report the case of 24-year-old man with fevers, headaches, and impaired consciousness who had been treated with glucocorticoids for a protein-losing gastroenteropathy. The cerebrospinal fluid analysis revealed cryptococcal meningitis. Computed tomography showed bilateral adrenal enlargement. A retrospective analysis revealed that the enlargement had been detected 5 months before admission and gradually increased. The enlargement was improved with antifungal therapy and normalized 6 months later. This is the first report describing morphological changes in the adrenal glands associated with cryptococcal meningitis. Adrenal enlargement by cryptococcosis can be improved without any abnormal findings, including calcifications, which may be a unique characteristic from other diseases, including tuberculosis.http://dx.doi.org/10.1155/2017/1543149 |
| spellingShingle | Yuka Muraoka Shintaro Iwama Hiroshi Arima Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis Case Reports in Endocrinology |
| title | Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis |
| title_full | Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis |
| title_fullStr | Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis |
| title_full_unstemmed | Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis |
| title_short | Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis |
| title_sort | normalization of bilateral adrenal gland enlargement after treatment for cryptococcosis |
| url | http://dx.doi.org/10.1155/2017/1543149 |
| work_keys_str_mv | AT yukamuraoka normalizationofbilateraladrenalglandenlargementaftertreatmentforcryptococcosis AT shintaroiwama normalizationofbilateraladrenalglandenlargementaftertreatmentforcryptococcosis AT hiroshiarima normalizationofbilateraladrenalglandenlargementaftertreatmentforcryptococcosis |