Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides

Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides

Introduction: Antimicrobial peptides (AMPs) are valuable alternatives to traditional antibiotics, possess a variety of potent biological activities and exhibit immunomodulatory effects that alleviate difficult-to-treat infections. Clarifying the structure-activity relationships of AMPs can direct th...

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Bibliographic Details
Main Authors: Heqian Zhang, Yihan Wang, Yanran Zhu, Pengtao Huang, Qiandi Gao, Xiaojie Li, Zhaoying Chen, Yu Liu, Jiakun Jiang, Yuan Gao, Jiaquan Huang, Zhiwei Qin
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Advanced Research
Subjects:
Machine learning
Genetic algorithm
Directed evolution
Antimicrobial peptide
Online Access:http://www.sciencedirect.com/science/article/pii/S209012322400078X
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