Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected Patient
A case of cotrimoxazole-induced hypoglycemia is described in a male patient infected with HIV. Ten days after initiating high dose cotrimoxazole for suspected Pneumocystis carinii pneumonia, the patient developed neuroglycopenic symptoms and diaphoresis. Blood glucose levels were repeatedly low, wit...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2001-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2001/848946 |
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| _version_ | 1832548034044493824 |
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| author | Christine A Hughes Constance L Chik Geoffrey D Taylor |
| author_facet | Christine A Hughes Constance L Chik Geoffrey D Taylor |
| author_sort | Christine A Hughes |
| collection | DOAJ |
| description | A case of cotrimoxazole-induced hypoglycemia is described in a male patient infected with HIV. Ten days after initiating high dose cotrimoxazole for suspected Pneumocystis carinii pneumonia, the patient developed neuroglycopenic symptoms and diaphoresis. Blood glucose levels were repeatedly low, with elevated insulin and C-peptide levels despite multiple intravenous bolus doses and infusions of dextrose. Hypoglycemia resolved after approximately 36 h of treatment with dextrose and discontinuation of cotrimoxazole. A review of reported cases of hypoglycemia associated with cotrimoxazole is provided, including information about onset, risk factors and possible mechanism. |
| format | Article |
| id | doaj-art-124e773f3e5e48de9368641de900ab24 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 2001-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-124e773f3e5e48de9368641de900ab242025-02-03T06:42:26ZengWileyCanadian Journal of Infectious Diseases1180-23322001-01-0112531431610.1155/2001/848946Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected PatientChristine A Hughes0Constance L Chik1Geoffrey D Taylor2Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, CanadaDivision of Endocrinology and Metabolism, University of Alberta, Edmonton, Alberta, CanadaDivision of Infectious Diseases, University of Alberta, Edmonton, Alberta, CanadaA case of cotrimoxazole-induced hypoglycemia is described in a male patient infected with HIV. Ten days after initiating high dose cotrimoxazole for suspected Pneumocystis carinii pneumonia, the patient developed neuroglycopenic symptoms and diaphoresis. Blood glucose levels were repeatedly low, with elevated insulin and C-peptide levels despite multiple intravenous bolus doses and infusions of dextrose. Hypoglycemia resolved after approximately 36 h of treatment with dextrose and discontinuation of cotrimoxazole. A review of reported cases of hypoglycemia associated with cotrimoxazole is provided, including information about onset, risk factors and possible mechanism.http://dx.doi.org/10.1155/2001/848946 |
| spellingShingle | Christine A Hughes Constance L Chik Geoffrey D Taylor Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected Patient Canadian Journal of Infectious Diseases |
| title | Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected Patient |
| title_full | Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected Patient |
| title_fullStr | Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected Patient |
| title_full_unstemmed | Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected Patient |
| title_short | Cotrimoxazole-Induced Hypoglycemia in an HIV-Infected Patient |
| title_sort | cotrimoxazole induced hypoglycemia in an hiv infected patient |
| url | http://dx.doi.org/10.1155/2001/848946 |
| work_keys_str_mv | AT christineahughes cotrimoxazoleinducedhypoglycemiainanhivinfectedpatient AT constancelchik cotrimoxazoleinducedhypoglycemiainanhivinfectedpatient AT geoffreydtaylor cotrimoxazoleinducedhypoglycemiainanhivinfectedpatient |