Order reduction for an RNA virus evolution model

A mathematical or computational model in evolutionary biologyshould necessary combine several comparatively fast processes,which actually drive natural selection and evolution, with a veryslow process of evolution. As a result, several very differenttime scales are simultaneously present in the mode...

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Bibliographic Details
Main Authors: Andrei Korobeinikov, Aleksei Archibasov, Vladimir Sobolev
Format: Article
Language:English
Published: AIMS Press 2015-05-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1007
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Summary:A mathematical or computational model in evolutionary biologyshould necessary combine several comparatively fast processes,which actually drive natural selection and evolution, with a veryslow process of evolution. As a result, several very differenttime scales are simultaneously present in the model; this makesits analytical study an extremely difficult task. However, thesignificant difference of the time scales implies the existence ofa possibility of the model order reduction through a process oftime separation. In this paper we conduct the procedure of modelorder reduction for a reasonably simple model of RNA virusevolution reducing the original system of three integro-partialderivative equations to a single equation. Computations confirmthat there is a good fit between the results for the original andreduced models.
ISSN:1551-0018