Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion
Studies in relation to blood conservation and responses to transfusion are scarce for ruminants. We evaluated the clinical manifestations of sheep that received a single homologous transfusion of whole blood, focusing on transfusion reactions. Eighteen adult sheep were subjected to a single phleboto...
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| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/734397 |
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| author | Rejane Santos Sousa Antonio Humberto Hamad Minervino Carolina Akiko Sato Cabral Araújo Frederico Augusto Mazzocca Lopes Rodrigues Francisco Leonardo Costa Oliveira Clara Satsuki Mori Janaina Larissa Rodrigues Zaminhan Thiago Rocha Moreira Isadora Karolina Freitas Sousa Enrico Lippi Ortolani Raimundo Alves Barrêto Júnior |
| author_facet | Rejane Santos Sousa Antonio Humberto Hamad Minervino Carolina Akiko Sato Cabral Araújo Frederico Augusto Mazzocca Lopes Rodrigues Francisco Leonardo Costa Oliveira Clara Satsuki Mori Janaina Larissa Rodrigues Zaminhan Thiago Rocha Moreira Isadora Karolina Freitas Sousa Enrico Lippi Ortolani Raimundo Alves Barrêto Júnior |
| author_sort | Rejane Santos Sousa |
| collection | DOAJ |
| description | Studies in relation to blood conservation and responses to transfusion are scarce for ruminants. We evaluated the clinical manifestations of sheep that received a single homologous transfusion of whole blood, focusing on transfusion reactions. Eighteen adult sheep were subjected to a single phlebotomy to withdraw 40% of the total blood volume, which was placed into CPDA-1 bags and then divided into G0, animals that received fresh blood, and G15 and G35, animals that received blood stored for 15 or 35 days, respectively. Clinical observations were recorded throughout the transfusion, whereas heart rate, respiratory rate, and rectal temperature were assessed at the following times: 24 hours after phlebotomy and before transfusion; 30 minutes, six, twelve, 24, 48, 72, and 96 hours and eight and 16 days after transfusion. All groups presented transfusion reactions, among which hyperthermia was the most frequent (50% of animals). Tachycardia occurred most frequently in the G35 animals (50% of them). During transfusion G35 animals presented more clinical manifestation (P<0.05). Transfusion of fresh or stored total blood improved the blood volume, but transfusion reactions occurred, demonstrating that a single transfusion of fresh or stored blood can cause inflammatory and febrile nonhemolytic transfusion reactions in sheep. |
| format | Article |
| id | doaj-art-11fd7bd0818c47ef8fda57a985ca5020 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-11fd7bd0818c47ef8fda57a985ca50202025-02-03T01:21:31ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/734397734397Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood TransfusionRejane Santos Sousa0Antonio Humberto Hamad Minervino1Carolina Akiko Sato Cabral Araújo2Frederico Augusto Mazzocca Lopes Rodrigues3Francisco Leonardo Costa Oliveira4Clara Satsuki Mori5Janaina Larissa Rodrigues Zaminhan6Thiago Rocha Moreira7Isadora Karolina Freitas Sousa8Enrico Lippi Ortolani9Raimundo Alves Barrêto Júnior10Department of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilInstitute of Biodiversity and Forest, Federal University of Western Pará, Avenida Vera Paz S/N, Salé, 68000-000 Santarém, PA, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Clinical Science, Faculty of Veterinary Medicine, University of Sao Paulo, Avenida Professor Orlando Marques de Paiva, 87 Cidade Universitária, 05508-270 São Paulo, SP, BrazilDepartment of Animal Science, Federal Rural University of the Semiarid Region, Avenida Francisco Mota, s/n Bairro Presidente Costa e Silva, 59625-900 Mossoró, RN, BrazilStudies in relation to blood conservation and responses to transfusion are scarce for ruminants. We evaluated the clinical manifestations of sheep that received a single homologous transfusion of whole blood, focusing on transfusion reactions. Eighteen adult sheep were subjected to a single phlebotomy to withdraw 40% of the total blood volume, which was placed into CPDA-1 bags and then divided into G0, animals that received fresh blood, and G15 and G35, animals that received blood stored for 15 or 35 days, respectively. Clinical observations were recorded throughout the transfusion, whereas heart rate, respiratory rate, and rectal temperature were assessed at the following times: 24 hours after phlebotomy and before transfusion; 30 minutes, six, twelve, 24, 48, 72, and 96 hours and eight and 16 days after transfusion. All groups presented transfusion reactions, among which hyperthermia was the most frequent (50% of animals). Tachycardia occurred most frequently in the G35 animals (50% of them). During transfusion G35 animals presented more clinical manifestation (P<0.05). Transfusion of fresh or stored total blood improved the blood volume, but transfusion reactions occurred, demonstrating that a single transfusion of fresh or stored blood can cause inflammatory and febrile nonhemolytic transfusion reactions in sheep.http://dx.doi.org/10.1155/2014/734397 |
| spellingShingle | Rejane Santos Sousa Antonio Humberto Hamad Minervino Carolina Akiko Sato Cabral Araújo Frederico Augusto Mazzocca Lopes Rodrigues Francisco Leonardo Costa Oliveira Clara Satsuki Mori Janaina Larissa Rodrigues Zaminhan Thiago Rocha Moreira Isadora Karolina Freitas Sousa Enrico Lippi Ortolani Raimundo Alves Barrêto Júnior Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion The Scientific World Journal |
| title | Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion |
| title_full | Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion |
| title_fullStr | Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion |
| title_full_unstemmed | Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion |
| title_short | Clinical Response and Transfusion Reactions of Sheep Subjected to Single Homologous Blood Transfusion |
| title_sort | clinical response and transfusion reactions of sheep subjected to single homologous blood transfusion |
| url | http://dx.doi.org/10.1155/2014/734397 |
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