Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies

Parkinson’s disease is one of the main reasons for neurological consultation in Spain. Due to the nature of the disease, it impacts patients, families, and caregivers. Parkinson’s disease is a degenerative disease with no cure, although second-line therapies have recently improved the quality of lif...

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Main Authors: Elisa Gomez-Inhiesto, María Teresa Acaiturri-Ayesta, Iker Ustarroz-Aguirre, Diana Camahuali, Maider Urtaran-Laresgoiti, Marisol Basabe-Aldecoa, Roberto Nuño-Solinís, Elena Urizar
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2020/9106026
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author Elisa Gomez-Inhiesto
María Teresa Acaiturri-Ayesta
Iker Ustarroz-Aguirre
Diana Camahuali
Maider Urtaran-Laresgoiti
Marisol Basabe-Aldecoa
Roberto Nuño-Solinís
Elena Urizar
author_facet Elisa Gomez-Inhiesto
María Teresa Acaiturri-Ayesta
Iker Ustarroz-Aguirre
Diana Camahuali
Maider Urtaran-Laresgoiti
Marisol Basabe-Aldecoa
Roberto Nuño-Solinís
Elena Urizar
author_sort Elisa Gomez-Inhiesto
collection DOAJ
description Parkinson’s disease is one of the main reasons for neurological consultation in Spain. Due to the nature of the disease, it impacts patients, families, and caregivers. Parkinson’s disease is a degenerative disease with no cure, although second-line therapies have recently improved the quality of life of patients in advanced stages. The aim of this study was to analyse the costs of the following therapies: deep brain stimulation (DBS), continuous duodenal levodopa/carbidopa infusion (CDLCI), and continuous subcutaneous apomorphine infusion (CSAI). The methodology used was based on real-world data obtained from an integrated healthcare organization in the Basque Country from 2016 to 2018. This bottom-up retrospective approach only took into account the healthcare perspective. The results revealed the annual cost over 3 years and the projected cost for an additional 2 years. The total costs for 5 years of treatment were as follows: €53,217 for DBS, €208,163 for CDLCI, and €170,591 for CSAI. These costs are in line with those found in the available literature on the subject. Additionally, the analysis provided details of the different costs incurred during intervention with the therapies and compared the costs to those reported in other studies.
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institution Kabale University
issn 2090-8083
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language English
publishDate 2020-01-01
publisher Wiley
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series Parkinson's Disease
spelling doaj-art-11ea4464744a4495917e83283371d94e2025-02-03T05:54:26ZengWileyParkinson's Disease2090-80832042-00802020-01-01202010.1155/2020/91060269106026Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line TherapiesElisa Gomez-Inhiesto0María Teresa Acaiturri-Ayesta1Iker Ustarroz-Aguirre2Diana Camahuali3Maider Urtaran-Laresgoiti4Marisol Basabe-Aldecoa5Roberto Nuño-Solinís6Elena Urizar7Dirección Económico-Financiera, Hospital Universitario Cruces—OSI Ezkerraldea Enkarterri Cruces, Barakaldo, Biscay, SpainDirección Económico-Financiera, Hospital Universitario Cruces—OSI Ezkerraldea Enkarterri Cruces, Barakaldo, Biscay, SpainDirección Económico-Financiera, Hospital Universitario Cruces—OSI Ezkerraldea Enkarterri Cruces, Barakaldo, Biscay, SpainDeusto Business School Health, University of Deusto, Bilbao, SpainDeusto Business School Health, University of Deusto, Bilbao, SpainDeusto Business School Health, University of Deusto, Bilbao, SpainDeusto Business School Health, University of Deusto, Bilbao, SpainDeusto Business School Health, University of Deusto, Bilbao, SpainParkinson’s disease is one of the main reasons for neurological consultation in Spain. Due to the nature of the disease, it impacts patients, families, and caregivers. Parkinson’s disease is a degenerative disease with no cure, although second-line therapies have recently improved the quality of life of patients in advanced stages. The aim of this study was to analyse the costs of the following therapies: deep brain stimulation (DBS), continuous duodenal levodopa/carbidopa infusion (CDLCI), and continuous subcutaneous apomorphine infusion (CSAI). The methodology used was based on real-world data obtained from an integrated healthcare organization in the Basque Country from 2016 to 2018. This bottom-up retrospective approach only took into account the healthcare perspective. The results revealed the annual cost over 3 years and the projected cost for an additional 2 years. The total costs for 5 years of treatment were as follows: €53,217 for DBS, €208,163 for CDLCI, and €170,591 for CSAI. These costs are in line with those found in the available literature on the subject. Additionally, the analysis provided details of the different costs incurred during intervention with the therapies and compared the costs to those reported in other studies.http://dx.doi.org/10.1155/2020/9106026
spellingShingle Elisa Gomez-Inhiesto
María Teresa Acaiturri-Ayesta
Iker Ustarroz-Aguirre
Diana Camahuali
Maider Urtaran-Laresgoiti
Marisol Basabe-Aldecoa
Roberto Nuño-Solinís
Elena Urizar
Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies
Parkinson's Disease
title Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies
title_full Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies
title_fullStr Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies
title_full_unstemmed Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies
title_short Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies
title_sort direct cost of parkinson s disease a real world data study of second line therapies
url http://dx.doi.org/10.1155/2020/9106026
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