Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether
Cetyl palmitate was produced by the esterification of palmitic acid with cetyl alcohol using n-hexane and ethyl ether as solvents and a commercial lipase as a catalyst. The effect of solvents to reagents mass ratio (0.5 : 1–3 : 1), percentage of n-hexane in the solvent mixture (0–100%), and reaction...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | International Journal of Chemical Engineering |
| Online Access: | http://dx.doi.org/10.1155/2024/4796291 |
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| author | Gustavo Gealh Maynara L. A. Santos Marcos L. Corazza Adrián Bonilla-Petriciolet Fernando A. P. Voll |
| author_facet | Gustavo Gealh Maynara L. A. Santos Marcos L. Corazza Adrián Bonilla-Petriciolet Fernando A. P. Voll |
| author_sort | Gustavo Gealh |
| collection | DOAJ |
| description | Cetyl palmitate was produced by the esterification of palmitic acid with cetyl alcohol using n-hexane and ethyl ether as solvents and a commercial lipase as a catalyst. The effect of solvents to reagents mass ratio (0.5 : 1–3 : 1), percentage of n-hexane in the solvent mixture (0–100%), and reaction temperature (25–55°C) on the reaction rate were evaluated for a fixed amount of enzyme (1 wt% related to the total mass of substrates) in an equimolar mixture of palmitic acid and cetyl alcohol. Temperature and n-hexane percentage in the solvent had positive effects on the reaction rate. The total solvent-to-reagent mass ratio showed a negative effect on the reaction rate when a solvent mixture rich in ethyl ether was used. The higher the concentration of n-hexane, the lower the effect of the mass ratio of solvents to reagents on the reaction rate. Although the amount of ethyl ether in the solvent mixture had a negative effect on the reaction rate, it had a positive effect on the solubility of the system, that is, the more ethyl ether in the mixture, the lower the solvent to reagents mass ratio required to ensure a homogeneous mixture. A ping-pong bi-bi mechanism-based model was proposed to represent the system kinetics and was well fitted to the experimental data. |
| format | Article |
| id | doaj-art-11e6fe7ed14242fdb1ae915042359561 |
| institution | Kabale University |
| issn | 1687-8078 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Chemical Engineering |
| spelling | doaj-art-11e6fe7ed14242fdb1ae9150423595612025-02-03T05:55:19ZengWileyInternational Journal of Chemical Engineering1687-80782024-01-01202410.1155/2024/4796291Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl EtherGustavo Gealh0Maynara L. A. Santos1Marcos L. Corazza2Adrián Bonilla-Petriciolet3Fernando A. P. Voll4Department of Chemical EngineeringDepartment of Chemical EngineeringDepartment of Chemical EngineeringDepartment of Chemical EngineeringDepartment of Chemical EngineeringCetyl palmitate was produced by the esterification of palmitic acid with cetyl alcohol using n-hexane and ethyl ether as solvents and a commercial lipase as a catalyst. The effect of solvents to reagents mass ratio (0.5 : 1–3 : 1), percentage of n-hexane in the solvent mixture (0–100%), and reaction temperature (25–55°C) on the reaction rate were evaluated for a fixed amount of enzyme (1 wt% related to the total mass of substrates) in an equimolar mixture of palmitic acid and cetyl alcohol. Temperature and n-hexane percentage in the solvent had positive effects on the reaction rate. The total solvent-to-reagent mass ratio showed a negative effect on the reaction rate when a solvent mixture rich in ethyl ether was used. The higher the concentration of n-hexane, the lower the effect of the mass ratio of solvents to reagents on the reaction rate. Although the amount of ethyl ether in the solvent mixture had a negative effect on the reaction rate, it had a positive effect on the solubility of the system, that is, the more ethyl ether in the mixture, the lower the solvent to reagents mass ratio required to ensure a homogeneous mixture. A ping-pong bi-bi mechanism-based model was proposed to represent the system kinetics and was well fitted to the experimental data.http://dx.doi.org/10.1155/2024/4796291 |
| spellingShingle | Gustavo Gealh Maynara L. A. Santos Marcos L. Corazza Adrián Bonilla-Petriciolet Fernando A. P. Voll Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether International Journal of Chemical Engineering |
| title | Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether |
| title_full | Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether |
| title_fullStr | Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether |
| title_full_unstemmed | Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether |
| title_short | Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether |
| title_sort | lipase catalyzed synthesis of cetyl palmitate in the presence of n hexane and ethyl ether |
| url | http://dx.doi.org/10.1155/2024/4796291 |
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