Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White Rats
Diabetes Mellitus is a metabolic disorder characterized by hyperglycemia caused by a decrease in insulin secretion. Sambiloto leaves (Andrographis paniculata (Burm.f.) Wall. Ex Ness) and bitter melon (Momordica charantia L) are types of plants that are used as regulators of blood sugar levels. The s...
Saved in:
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | Indonesian |
Published: |
Politeknik Kesehatan Tanjung Karang
2023-11-01
|
Series: | Jurnal Kesehatan |
Subjects: | |
Online Access: | https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/4152 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832591283809419264 |
---|---|
author | Vicko Suswidiantoro Mida Pratiwi Wina Safutri Ahmad Bayu Satriawan Yuhana Sari |
author_facet | Vicko Suswidiantoro Mida Pratiwi Wina Safutri Ahmad Bayu Satriawan Yuhana Sari |
author_sort | Vicko Suswidiantoro |
collection | DOAJ |
description | Diabetes Mellitus is a metabolic disorder characterized by hyperglycemia caused by a decrease in insulin secretion. Sambiloto leaves (Andrographis paniculata (Burm.f.) Wall. Ex Ness) and bitter melon (Momordica charantia L) are types of plants that are used as regulators of blood sugar levels. The study aimed to determine the effectiveness and effective comparative doses in the combination of sambiloto leaf extract (Andrographis paniculata (Burm.f.) Wall. Ex Ness) and bitter melon (Momordica charantia L) on alloxan-induced Wistar white rats. This study is experimental research with a pre and post-control group design, using a sample of 24 subjects. The data analysis in this study employed normality and homogeneity tests, obtaining a significance result of p>0.05. The development of the ANOVA test revealed a significant value of p |
format | Article |
id | doaj-art-11c8741d6e0941a99c171a9ba9b4ee73 |
institution | Kabale University |
issn | 2086-7751 2548-5695 |
language | Indonesian |
publishDate | 2023-11-01 |
publisher | Politeknik Kesehatan Tanjung Karang |
record_format | Article |
series | Jurnal Kesehatan |
spelling | doaj-art-11c8741d6e0941a99c171a9ba9b4ee732025-01-22T14:13:51ZindPoliteknik Kesehatan Tanjung KarangJurnal Kesehatan2086-77512548-56952023-11-0114350550910.26630/jk.v14i3.41523479Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White RatsVicko Suswidiantoro0Mida Pratiwi1Wina Safutri2Ahmad Bayu Satriawan3Yuhana Sari4Aisyah University of PringsewuAisyah University of PringsewuAisyah University of PringsewuAisyah University of PringsewuAisyah University of PringsewuDiabetes Mellitus is a metabolic disorder characterized by hyperglycemia caused by a decrease in insulin secretion. Sambiloto leaves (Andrographis paniculata (Burm.f.) Wall. Ex Ness) and bitter melon (Momordica charantia L) are types of plants that are used as regulators of blood sugar levels. The study aimed to determine the effectiveness and effective comparative doses in the combination of sambiloto leaf extract (Andrographis paniculata (Burm.f.) Wall. Ex Ness) and bitter melon (Momordica charantia L) on alloxan-induced Wistar white rats. This study is experimental research with a pre and post-control group design, using a sample of 24 subjects. The data analysis in this study employed normality and homogeneity tests, obtaining a significance result of p>0.05. The development of the ANOVA test revealed a significant value of phttps://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/4152alloxanblood sugar leveldiabetes mellitus. |
spellingShingle | Vicko Suswidiantoro Mida Pratiwi Wina Safutri Ahmad Bayu Satriawan Yuhana Sari Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White Rats Jurnal Kesehatan alloxan blood sugar level diabetes mellitus. |
title | Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White Rats |
title_full | Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White Rats |
title_fullStr | Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White Rats |
title_full_unstemmed | Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White Rats |
title_short | Anti-Hyperglycemic Effect of Combination Etanolic Extract of Sambiloto (Andrographis paniculata) and Bitter Melon Fruit (Momordica charantia L) on Alloxan-Induced Wistar White Rats |
title_sort | anti hyperglycemic effect of combination etanolic extract of sambiloto andrographis paniculata and bitter melon fruit momordica charantia l on alloxan induced wistar white rats |
topic | alloxan blood sugar level diabetes mellitus. |
url | https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/4152 |
work_keys_str_mv | AT vickosuswidiantoro antihyperglycemiceffectofcombinationetanolicextractofsambilotoandrographispaniculataandbittermelonfruitmomordicacharantialonalloxaninducedwistarwhiterats AT midapratiwi antihyperglycemiceffectofcombinationetanolicextractofsambilotoandrographispaniculataandbittermelonfruitmomordicacharantialonalloxaninducedwistarwhiterats AT winasafutri antihyperglycemiceffectofcombinationetanolicextractofsambilotoandrographispaniculataandbittermelonfruitmomordicacharantialonalloxaninducedwistarwhiterats AT ahmadbayusatriawan antihyperglycemiceffectofcombinationetanolicextractofsambilotoandrographispaniculataandbittermelonfruitmomordicacharantialonalloxaninducedwistarwhiterats AT yuhanasari antihyperglycemiceffectofcombinationetanolicextractofsambilotoandrographispaniculataandbittermelonfruitmomordicacharantialonalloxaninducedwistarwhiterats |