Liquid Chromatography-Tandem Mass Spectrometric Assay for Determination of Stavudine in Human Plasma

A LC-MS/MS method for determination of stavudine in human plasma was established and validated, and it was applied to the pharmaceutical formulations bioequivalence study. 0.5 mL plasma sample was extracted by liquid-liquid extraction. Stavudine was detected by a LC-MS/MS system. The pharmacokinetic...

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Bibliographic Details
Main Author: Fengdan Jin
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Spectroscopy
Online Access:http://dx.doi.org/10.1155/2014/517089
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