Targeting RTKs/nRTKs as promising therapeutic strategies for the treatment of triple-negative breast cancer: evidence from clinical trials

Targeting RTKs/nRTKs as promising therapeutic strategies for the treatment of triple-negative breast cancer: evidence from clinical trials

Abstract The extensive heterogeneity and the limited availability of effective targeted therapies contribute to the challenging prognosis and restricted survival observed in triple-negative breast cancer (TNBC). Recent research indicates the aberrant expression of diverse tyrosine kinases (TKs) with...

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Main Authors: Kasshish Mehta, Mangala Hegde, Sosmitha Girisa, Ravichandran Vishwa, Mohammed S. Alqahtani, Mohamed Abbas, Mehdi Shakibaei, Gautam Sethi, Ajaikumar B. Kunnumakkara
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Military Medical Research
Subjects:
Triple-negative breast cancer (TNBC)
Tyrosine kinase
Clinical trial
Personalised medicine
Genetic diversity
Patient stratification
Online Access:https://doi.org/10.1186/s40779-024-00582-z
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