Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study
The cerebellum and the hippocampus are key structures for the acquisition of conditioned eyeblink responses. Whereas the cerebellum seems to be crucial for all types of eyeblink conditioning, the hippocampus appears to be involved only in complex types of learning. We conducted a differential condit...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2003-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/NP.2003.291 |
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| _version_ | 1832547482351960064 |
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| author | Peter Kirsch Caroline Achenbach Martina Kirsch Matthias Heinzmann Anne Schienle Dieter Vaitl |
| author_facet | Peter Kirsch Caroline Achenbach Martina Kirsch Matthias Heinzmann Anne Schienle Dieter Vaitl |
| author_sort | Peter Kirsch |
| collection | DOAJ |
| description | The cerebellum and the hippocampus are
key structures for the acquisition of conditioned
eyeblink responses. Whereas the cerebellum
seems to be crucial for all types of eyeblink
conditioning, the hippocampus appears to be
involved only in complex types of learning. We
conducted a differential conditioning study to
explore the suitability of the design for
magnetencephalography (MEG). In addition,
we compared cerebellar and hippocampal
activation during differential delay and trace
conditioning. Comparable conditioning effects
were seen in both conditions, but a greater
resistance to extinction for trace conditioning.
Brain activation differed between paradigms:
delay conditioning provoked activation only in
the cerebellum and trace conditioning only in
the hippocampus. The results reflect differential
brain activation patterns during the two types
of eyeblink conditioning. |
| format | Article |
| id | doaj-art-11526a00f5ce4169b83058864427bb9e |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2003-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-11526a00f5ce4169b83058864427bb9e2025-02-03T06:44:27ZengWileyNeural Plasticity2090-59041687-54432003-01-0110429130110.1155/NP.2003.291Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG StudyPeter Kirsch0Caroline Achenbach1Martina Kirsch2Matthias Heinzmann3Anne Schienle4Dieter Vaitl5Department of Clinical & Physiological Psychology, GermanyDepartment of Clinical & Physiological Psychology, GermanyDepartment of Neurology, University of Heidelberg, GermanyDepartment of psychology, University of Heidelberg, GermanyDepartment of Clinical & Physiological Psychology, GermanyDepartment of Clinical & Physiological Psychology, GermanyThe cerebellum and the hippocampus are key structures for the acquisition of conditioned eyeblink responses. Whereas the cerebellum seems to be crucial for all types of eyeblink conditioning, the hippocampus appears to be involved only in complex types of learning. We conducted a differential conditioning study to explore the suitability of the design for magnetencephalography (MEG). In addition, we compared cerebellar and hippocampal activation during differential delay and trace conditioning. Comparable conditioning effects were seen in both conditions, but a greater resistance to extinction for trace conditioning. Brain activation differed between paradigms: delay conditioning provoked activation only in the cerebellum and trace conditioning only in the hippocampus. The results reflect differential brain activation patterns during the two types of eyeblink conditioning.http://dx.doi.org/10.1155/NP.2003.291 |
| spellingShingle | Peter Kirsch Caroline Achenbach Martina Kirsch Matthias Heinzmann Anne Schienle Dieter Vaitl Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study Neural Plasticity |
| title | Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study |
| title_full | Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study |
| title_fullStr | Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study |
| title_full_unstemmed | Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study |
| title_short | Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study |
| title_sort | cerebellar and hippocampal activation during eyeblink conditioning depends on the experimental paradigm a meg study |
| url | http://dx.doi.org/10.1155/NP.2003.291 |
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