Cerebellar and Hippocampal Activation During Eyeblink Conditioning Depends on the Experimental Paradigm: A MEG Study
The cerebellum and the hippocampus are key structures for the acquisition of conditioned eyeblink responses. Whereas the cerebellum seems to be crucial for all types of eyeblink conditioning, the hippocampus appears to be involved only in complex types of learning. We conducted a differential condit...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2003-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/NP.2003.291 |
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| Summary: | The cerebellum and the hippocampus are
key structures for the acquisition of conditioned
eyeblink responses. Whereas the cerebellum
seems to be crucial for all types of eyeblink
conditioning, the hippocampus appears to be
involved only in complex types of learning. We
conducted a differential conditioning study to
explore the suitability of the design for
magnetencephalography (MEG). In addition,
we compared cerebellar and hippocampal
activation during differential delay and trace
conditioning. Comparable conditioning effects
were seen in both conditions, but a greater
resistance to extinction for trace conditioning.
Brain activation differed between paradigms:
delay conditioning provoked activation only in
the cerebellum and trace conditioning only in
the hippocampus. The results reflect differential
brain activation patterns during the two types
of eyeblink conditioning. |
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| ISSN: | 2090-5904 1687-5443 |