Vision After Early-Onset Lesions of the Occipital Cortex: II. Physiological Studies
In one of two patients (MS and FJ) with bilateral, early-onset lesion of the primary visual cortex, Kiper et al. (2002) observed a considerable degree of functional recovery. To clarify the physiological mechanisms involved in the recovery, we used fMRI and quantitative EEG to study both patients. T...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2002-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/NP.2002.27 |
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| _version_ | 1832556313884753920 |
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| author | M. G. Knyazeva P. Maeder D. C. Kiper T. Deonna G. M. Innocenti |
| author_facet | M. G. Knyazeva P. Maeder D. C. Kiper T. Deonna G. M. Innocenti |
| author_sort | M. G. Knyazeva |
| collection | DOAJ |
| description | In one of two patients (MS and FJ) with
bilateral, early-onset lesion of the primary
visual cortex, Kiper et al. (2002) observed
a considerable degree of functional recovery. To
clarify the physiological mechanisms involved
in the recovery, we used fMRI and quantitative
EEG to study both patients. The fMRI
investigations indicated that in both patients,
isolated islands of the primary visual cortex are
functioning, in the right hemisphere in MS and
in the left in FJ. The functional recovery
observed in MS roughly correlated with the
functional maturation of interhemispheric
connections and might reflect the role of corticocortical connectivity in visual perception. The
functionality of interhemispheric connections
was assessed by analyzing the changes in
occipital inter-hemispheric coherence of EEG
signals (ICoh) evoked by moving gratings. In
the patient MS, this ICoh response was present
at 7:11 y and was more mature at 9:2 y. In the
more visually mpaired patient, FJ, a consistent
increase in ICoh to visual stimuli could not be
obtained, possibly because of the later occurrence
of the lesion. |
| format | Article |
| id | doaj-art-114e09c37d144570a8a4f20d7aa77787 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2002-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-114e09c37d144570a8a4f20d7aa777872025-02-03T05:45:36ZengWileyNeural Plasticity2090-59041687-54432002-01-0191274010.1155/NP.2002.27Vision After Early-Onset Lesions of the Occipital Cortex: II. Physiological StudiesM. G. Knyazeva0P. Maeder1D. C. Kiper2T. Deonna3G. M. Innocenti4Institut de Biologie Cellulaire et de Morphologie, University of Lausanne, SwitzerlandDept. of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, SwitzerlandInstitut de Biologie Cellulaire et de Morphologie, University of Lausanne, SwitzerlandDept. of Pediatric Neurology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, SwitzerlandDivision of Neuroanatomy and Brain Development, Dept. of Neuroscience, Karolinska Institutet, Stockholm S-17177, SwedenIn one of two patients (MS and FJ) with bilateral, early-onset lesion of the primary visual cortex, Kiper et al. (2002) observed a considerable degree of functional recovery. To clarify the physiological mechanisms involved in the recovery, we used fMRI and quantitative EEG to study both patients. The fMRI investigations indicated that in both patients, isolated islands of the primary visual cortex are functioning, in the right hemisphere in MS and in the left in FJ. The functional recovery observed in MS roughly correlated with the functional maturation of interhemispheric connections and might reflect the role of corticocortical connectivity in visual perception. The functionality of interhemispheric connections was assessed by analyzing the changes in occipital inter-hemispheric coherence of EEG signals (ICoh) evoked by moving gratings. In the patient MS, this ICoh response was present at 7:11 y and was more mature at 9:2 y. In the more visually mpaired patient, FJ, a consistent increase in ICoh to visual stimuli could not be obtained, possibly because of the later occurrence of the lesion.http://dx.doi.org/10.1155/NP.2002.27 |
| spellingShingle | M. G. Knyazeva P. Maeder D. C. Kiper T. Deonna G. M. Innocenti Vision After Early-Onset Lesions of the Occipital Cortex: II. Physiological Studies Neural Plasticity |
| title | Vision After Early-Onset Lesions of the Occipital Cortex:
II. Physiological Studies |
| title_full | Vision After Early-Onset Lesions of the Occipital Cortex:
II. Physiological Studies |
| title_fullStr | Vision After Early-Onset Lesions of the Occipital Cortex:
II. Physiological Studies |
| title_full_unstemmed | Vision After Early-Onset Lesions of the Occipital Cortex:
II. Physiological Studies |
| title_short | Vision After Early-Onset Lesions of the Occipital Cortex:
II. Physiological Studies |
| title_sort | vision after early onset lesions of the occipital cortex ii physiological studies |
| url | http://dx.doi.org/10.1155/NP.2002.27 |
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