Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered

Objective. To analyze the safety and efficacy of high-myopic PRK as an alternative to LASIK surgery in patients with a high preoperative percentage tissue altered (PTA). Design. Retrospective interventional case series. Participants. Charts of 256 consecutive eyes that underwent PRK with application...

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Main Authors: Nir Sorkin, Amir Rosenblatt, David Smadja, Eyal Cohen, Marcony R. Santhiago, David Varssano, Yossi Yatziv
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2019/6513143
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author Nir Sorkin
Amir Rosenblatt
David Smadja
Eyal Cohen
Marcony R. Santhiago
David Varssano
Yossi Yatziv
author_facet Nir Sorkin
Amir Rosenblatt
David Smadja
Eyal Cohen
Marcony R. Santhiago
David Varssano
Yossi Yatziv
author_sort Nir Sorkin
collection DOAJ
description Objective. To analyze the safety and efficacy of high-myopic PRK as an alternative to LASIK surgery in patients with a high preoperative percentage tissue altered (PTA). Design. Retrospective interventional case series. Participants. Charts of 256 consecutive eyes that underwent PRK with application of mitomycin-C 0.02% for high myopia were retrospectively reviewed. Methods. Refractive (refraction and refractive accuracy) and visual outcomes (uncorrected and corrected visual acuities), as well as occurrence of haze in the eyes with preoperative PTA expected to be higher than 40% with a 110-micron flap if undergoing LASIK surgery, were analyzed. Results. Mean follow-up was 7.3 ± 4.8 months. A total of 187 of 256 eyes (73.0%) were included in the analysis because they were expected to have a PTA greater than 40%, should they have undergone LASIK surgery. The actual mean PTA of those eyes following PRK was 31.8 ± 2.2%, and none had a PTA ≥ 40%. UDVA of 20/16, 20/20, and 20/25 or better was achieved in 1.2% (2 eyes), 65.5% (112 eyes), and 85.4% (146 eyes), respectively. The percentage of eyes with postoperative SE within ±0.5 D and ±1.0 D of planned SE was 71% and 93%, respectively. None of the eyes lost 2 or more lines of CDVA. The rate of stromal haze, managed successfully with topical steroids only, was 4.8%. Conclusion. High-myopic PRK with application of mitomycin-C in the eyes at risk of developing ectasia because of high preoperative PTA was demonstrated to be a safe and effective alternative to the LASIK procedure.
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spelling doaj-art-1133d1d6b3d64673a60bc3196c9cb7ae2025-02-03T06:11:34ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/65131436513143Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue AlteredNir Sorkin0Amir Rosenblatt1David Smadja2Eyal Cohen3Marcony R. Santhiago4David Varssano5Yossi Yatziv6Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Ophthalmology, Federal University of Rio de Janeiro, Rio De Janeiro, BrazilDepartment of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelObjective. To analyze the safety and efficacy of high-myopic PRK as an alternative to LASIK surgery in patients with a high preoperative percentage tissue altered (PTA). Design. Retrospective interventional case series. Participants. Charts of 256 consecutive eyes that underwent PRK with application of mitomycin-C 0.02% for high myopia were retrospectively reviewed. Methods. Refractive (refraction and refractive accuracy) and visual outcomes (uncorrected and corrected visual acuities), as well as occurrence of haze in the eyes with preoperative PTA expected to be higher than 40% with a 110-micron flap if undergoing LASIK surgery, were analyzed. Results. Mean follow-up was 7.3 ± 4.8 months. A total of 187 of 256 eyes (73.0%) were included in the analysis because they were expected to have a PTA greater than 40%, should they have undergone LASIK surgery. The actual mean PTA of those eyes following PRK was 31.8 ± 2.2%, and none had a PTA ≥ 40%. UDVA of 20/16, 20/20, and 20/25 or better was achieved in 1.2% (2 eyes), 65.5% (112 eyes), and 85.4% (146 eyes), respectively. The percentage of eyes with postoperative SE within ±0.5 D and ±1.0 D of planned SE was 71% and 93%, respectively. None of the eyes lost 2 or more lines of CDVA. The rate of stromal haze, managed successfully with topical steroids only, was 4.8%. Conclusion. High-myopic PRK with application of mitomycin-C in the eyes at risk of developing ectasia because of high preoperative PTA was demonstrated to be a safe and effective alternative to the LASIK procedure.http://dx.doi.org/10.1155/2019/6513143
spellingShingle Nir Sorkin
Amir Rosenblatt
David Smadja
Eyal Cohen
Marcony R. Santhiago
David Varssano
Yossi Yatziv
Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered
Journal of Ophthalmology
title Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered
title_full Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered
title_fullStr Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered
title_full_unstemmed Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered
title_short Early Refractive and Clinical Outcomes of High-Myopic Photorefractive Keratectomy as an Alternative to LASIK Surgery in Eyes with High Preoperative Percentage of Tissue Altered
title_sort early refractive and clinical outcomes of high myopic photorefractive keratectomy as an alternative to lasik surgery in eyes with high preoperative percentage of tissue altered
url http://dx.doi.org/10.1155/2019/6513143
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