A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature
A case of a glomus tumor originating from the lung is reported. A 43-year-old female had undergone resection of a right lung tumor following a clinical diagnosis of carcinoid, sclerosing hemangioma, or other sarcoma. Histologically, the tumor comprised uniform small round to oval cells with centrall...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2012/782304 |
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| _version_ | 1832559328646660096 |
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| author | Yasushi Ariizumi Hirotaka Koizumi Masahiro Hoshikawa Takuo Shinmyo Kouji Ando Atsushi Mochizuki Ayako Tateishi Masatomo Doi Mieko Funatsu Ichirou Maeda Masayuki Takagi |
| author_facet | Yasushi Ariizumi Hirotaka Koizumi Masahiro Hoshikawa Takuo Shinmyo Kouji Ando Atsushi Mochizuki Ayako Tateishi Masatomo Doi Mieko Funatsu Ichirou Maeda Masayuki Takagi |
| author_sort | Yasushi Ariizumi |
| collection | DOAJ |
| description | A case of a glomus tumor originating from the lung is reported. A 43-year-old female had undergone resection of a right lung tumor following a clinical diagnosis of carcinoid, sclerosing hemangioma, or other sarcoma. Histologically, the tumor comprised uniform small round to oval cells with centrally located nucleus, a clear cytoplasm, and apparent cell borders. The tumor also showed a focally hemangiopericytomatous pattern with irregularly branching or dilated vessels. Electron microscopy revealed smooth muscle differentiation of the tumor cells. Immunostaining further revealed that the tumor cells expressed smooth muscle actin, h-caldesmon, muscle specific actin (HHF-35), but not cytokeratin, epithelial membrane antigen, synaptophysin, or chromogranin A. Based on these findings, a diagnosis of primary pulmonary glomus tumor was established. Glomus tumors of the lung are very rare and only 21 cases have been reported to date. The histological features of the present tumor and the relevant literature are discussed. |
| format | Article |
| id | doaj-art-110d6a2a21ff4642aa4dcca388f6d29b |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-110d6a2a21ff4642aa4dcca388f6d29b2025-02-03T01:30:17ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/782304782304A Primary Pulmonary Glomus Tumor: A Case Report and Review of the LiteratureYasushi Ariizumi0Hirotaka Koizumi1Masahiro Hoshikawa2Takuo Shinmyo3Kouji Ando4Atsushi Mochizuki5Ayako Tateishi6Masatomo Doi7Mieko Funatsu8Ichirou Maeda9Masayuki Takagi10Department of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Respiratory Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Respiratory Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Respiratory Surgery, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae, Kawasaki 216-8511, JapanA case of a glomus tumor originating from the lung is reported. A 43-year-old female had undergone resection of a right lung tumor following a clinical diagnosis of carcinoid, sclerosing hemangioma, or other sarcoma. Histologically, the tumor comprised uniform small round to oval cells with centrally located nucleus, a clear cytoplasm, and apparent cell borders. The tumor also showed a focally hemangiopericytomatous pattern with irregularly branching or dilated vessels. Electron microscopy revealed smooth muscle differentiation of the tumor cells. Immunostaining further revealed that the tumor cells expressed smooth muscle actin, h-caldesmon, muscle specific actin (HHF-35), but not cytokeratin, epithelial membrane antigen, synaptophysin, or chromogranin A. Based on these findings, a diagnosis of primary pulmonary glomus tumor was established. Glomus tumors of the lung are very rare and only 21 cases have been reported to date. The histological features of the present tumor and the relevant literature are discussed.http://dx.doi.org/10.1155/2012/782304 |
| spellingShingle | Yasushi Ariizumi Hirotaka Koizumi Masahiro Hoshikawa Takuo Shinmyo Kouji Ando Atsushi Mochizuki Ayako Tateishi Masatomo Doi Mieko Funatsu Ichirou Maeda Masayuki Takagi A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature Case Reports in Pathology |
| title | A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature |
| title_full | A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature |
| title_fullStr | A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature |
| title_full_unstemmed | A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature |
| title_short | A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature |
| title_sort | primary pulmonary glomus tumor a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2012/782304 |
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