Evans Syndrome Associated with Pregnancy and COVID-19 Infection

Background. Evans syndrome (ES) is a chronic autoimmune disease characterized by autoimmune hemolytic anemia along with immune thrombocytopenic purpura. Few case reports of ES in pregnancy have been published, and ES may be difficult to distinguish from other diagnoses more common in pregnancy. Guid...

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Main Authors: Gayathri Vadlamudi, Leah Hong, Madhurima Keerthy
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2020/8862545
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author Gayathri Vadlamudi
Leah Hong
Madhurima Keerthy
author_facet Gayathri Vadlamudi
Leah Hong
Madhurima Keerthy
author_sort Gayathri Vadlamudi
collection DOAJ
description Background. Evans syndrome (ES) is a chronic autoimmune disease characterized by autoimmune hemolytic anemia along with immune thrombocytopenic purpura. Few case reports of ES in pregnancy have been published, and ES may be difficult to distinguish from other diagnoses more common in pregnancy. Guidelines for treatment of ES are not well-defined. Case. A 23-year-old multigravid woman in active labor was found to have severe anemia and thrombocytopenia. She was diagnosed with ES and started on immunosuppressive treatments for persistent immune thrombocytopenic purpura. In the postpartum period, she was found to have coronavirus (COVID-19) infection and acute pulmonary embolism. Conclusion. Evans syndrome is a challenge to diagnose in pregnancy and poses important considerations for intrapartum and postpartum management.
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-10f9c6ee9f2742c59c8a57163c8cb49c2025-02-03T06:43:45ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922020-01-01202010.1155/2020/88625458862545Evans Syndrome Associated with Pregnancy and COVID-19 InfectionGayathri Vadlamudi0Leah Hong1Madhurima Keerthy2Department of Obstetrics and Gynecology, Henry Ford Hospital, Detroit, MI, USADepartment of Obstetrics and Gynecology, Henry Ford Hospital, Detroit, MI, USADepartment of Obstetrics and Gynecology, Henry Ford Hospital, Detroit, MI, USABackground. Evans syndrome (ES) is a chronic autoimmune disease characterized by autoimmune hemolytic anemia along with immune thrombocytopenic purpura. Few case reports of ES in pregnancy have been published, and ES may be difficult to distinguish from other diagnoses more common in pregnancy. Guidelines for treatment of ES are not well-defined. Case. A 23-year-old multigravid woman in active labor was found to have severe anemia and thrombocytopenia. She was diagnosed with ES and started on immunosuppressive treatments for persistent immune thrombocytopenic purpura. In the postpartum period, she was found to have coronavirus (COVID-19) infection and acute pulmonary embolism. Conclusion. Evans syndrome is a challenge to diagnose in pregnancy and poses important considerations for intrapartum and postpartum management.http://dx.doi.org/10.1155/2020/8862545
spellingShingle Gayathri Vadlamudi
Leah Hong
Madhurima Keerthy
Evans Syndrome Associated with Pregnancy and COVID-19 Infection
Case Reports in Obstetrics and Gynecology
title Evans Syndrome Associated with Pregnancy and COVID-19 Infection
title_full Evans Syndrome Associated with Pregnancy and COVID-19 Infection
title_fullStr Evans Syndrome Associated with Pregnancy and COVID-19 Infection
title_full_unstemmed Evans Syndrome Associated with Pregnancy and COVID-19 Infection
title_short Evans Syndrome Associated with Pregnancy and COVID-19 Infection
title_sort evans syndrome associated with pregnancy and covid 19 infection
url http://dx.doi.org/10.1155/2020/8862545
work_keys_str_mv AT gayathrivadlamudi evanssyndromeassociatedwithpregnancyandcovid19infection
AT leahhong evanssyndromeassociatedwithpregnancyandcovid19infection
AT madhurimakeerthy evanssyndromeassociatedwithpregnancyandcovid19infection