3D QSAR Studies of DAMNI Analogs as Possible Non-nucleoside Reverse Transcriptase Inhibitors

The non-nucleoside inhibitors of HIV-1-reverse transcriptase (NNRTIs) are an important class of drugs employed in antiviral therapy. Recently, a novel family of NNRTIs commonly referred to as 1-[2-diarylmethoxy] ethyl) 2-methyl-5-nitroimidazoles (DAMNI) derivatives have been discovered. The 3D-QSAR...

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Bibliographic Details
Main Authors: S. Ganguly, V. Gopalakrishnan
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2008/712930
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