Developing muscarinic receptor M1 classification models utilizing transfer learning and generative AI techniques
Abstract Muscarinic receptor subtype 1 (M1) is a G protein-coupled receptor (GPCR) and a key pharmacological target for peripheral neuropathy, chronic obstructive pulmonary disease, nerve agent exposures, and cognitive disorders. Screening and identifying compounds with potential to interact with M1...
Saved in:
| Main Authors: | Souvik Dey, Anders Wallqvist, Mohamed Diwan M. AbdulHameed |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-00972-w |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
MONSTROUS: a web-based chemical-transporter interaction profiler
by: Mohamed Diwan M. AbdulHameed, et al.
Published: (2025-02-01) -
Downstream Signaling of Muscarinic M4 Receptors Is Regulated by Receptor Density and Cellular Environment
by: Madeleine Merz, et al.
Published: (2025-06-01) -
Is muscarinic receptor agonist effective and tolerant for schizophrenia?
by: Xiaonan Guo, et al.
Published: (2025-04-01) -
The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection.
by: Matthew Darby, et al.
Published: (2015-01-01) -
Characterization of Prejunctional Muscarinic Receptors: Effects on the Release of VIP and Functional Responses and Receptor Expression in the Ovine Submandibular Gland
by: Anders T. Ryberg, et al.
Published: (2009-01-01)