Thyroid Hemiagenesis Associated with Hyperthyroidism

Thyroid hemiagenesis (TH), very rare congenital anomaly, is generally asymptomatic. We report two cases of TH with hyperthyroidism. Case One. The patient presented with signs and symptoms of thyrotoxicosis. Physical examination revealed asymmetric nodular goitre at right lobe. Biochemical analysis r...

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Main Authors: Gunay Gurleyik, Emin Gurleyik
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2015/829712
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author Gunay Gurleyik
Emin Gurleyik
author_facet Gunay Gurleyik
Emin Gurleyik
author_sort Gunay Gurleyik
collection DOAJ
description Thyroid hemiagenesis (TH), very rare congenital anomaly, is generally asymptomatic. We report two cases of TH with hyperthyroidism. Case One. The patient presented with signs and symptoms of thyrotoxicosis. Physical examination revealed asymmetric nodular goitre at right lobe. Biochemical analysis revealed the diagnosis of hyperthyroidism. Ultrasound showed multinodular hypertrophy in the right lobe and absence of the left lobe. Nuclear scan, confirming absence of the left lobe, showed hot nodules in the right one. The diagnosis was toxic multinodular goitre. Case Two. The thyroid was not palpable in this patient presented with signs and symptoms of thyrotoxicosis. Biochemical analysis revealed the diagnosis of autoimmune thyrotoxicosis. Ultrasound showed mild diffuse hyperplasia of the right lobe and agenesis of the left lobe. Nuclear scan, confirming absence of the left lobe, showed increasing diffuse uptake of radiotracer in the right one. The diagnosis was Graves’ disease in this patient. After antithyroid medication, the patients were surgically treated with total excision of the thyroid tissue. TH is sometimes associated with disorders of the thyroid. Hyperthyroidism makes TH cases symptomatic. During evaluation of patients, ultrasound and nuclear scan usually report agenesis of one lobe and establish the diagnosis of TH. The surgical treatment is total removal of hyperactive tissue and total excision of the remaining lobe.
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spelling doaj-art-10e0d3012cfd494abd6ae55ac9a8e6142025-02-03T01:11:32ZengWileyCase Reports in Otolaryngology2090-67652090-67732015-01-01201510.1155/2015/829712829712Thyroid Hemiagenesis Associated with HyperthyroidismGunay Gurleyik0Emin Gurleyik1Department of Surgery, Haydarpasa Numune Education and Research Hospital, 34668 Istanbul, TurkeyDepartment of Surgery, Düzce University Faculty of Medicine, 81650 Düzce, TurkeyThyroid hemiagenesis (TH), very rare congenital anomaly, is generally asymptomatic. We report two cases of TH with hyperthyroidism. Case One. The patient presented with signs and symptoms of thyrotoxicosis. Physical examination revealed asymmetric nodular goitre at right lobe. Biochemical analysis revealed the diagnosis of hyperthyroidism. Ultrasound showed multinodular hypertrophy in the right lobe and absence of the left lobe. Nuclear scan, confirming absence of the left lobe, showed hot nodules in the right one. The diagnosis was toxic multinodular goitre. Case Two. The thyroid was not palpable in this patient presented with signs and symptoms of thyrotoxicosis. Biochemical analysis revealed the diagnosis of autoimmune thyrotoxicosis. Ultrasound showed mild diffuse hyperplasia of the right lobe and agenesis of the left lobe. Nuclear scan, confirming absence of the left lobe, showed increasing diffuse uptake of radiotracer in the right one. The diagnosis was Graves’ disease in this patient. After antithyroid medication, the patients were surgically treated with total excision of the thyroid tissue. TH is sometimes associated with disorders of the thyroid. Hyperthyroidism makes TH cases symptomatic. During evaluation of patients, ultrasound and nuclear scan usually report agenesis of one lobe and establish the diagnosis of TH. The surgical treatment is total removal of hyperactive tissue and total excision of the remaining lobe.http://dx.doi.org/10.1155/2015/829712
spellingShingle Gunay Gurleyik
Emin Gurleyik
Thyroid Hemiagenesis Associated with Hyperthyroidism
Case Reports in Otolaryngology
title Thyroid Hemiagenesis Associated with Hyperthyroidism
title_full Thyroid Hemiagenesis Associated with Hyperthyroidism
title_fullStr Thyroid Hemiagenesis Associated with Hyperthyroidism
title_full_unstemmed Thyroid Hemiagenesis Associated with Hyperthyroidism
title_short Thyroid Hemiagenesis Associated with Hyperthyroidism
title_sort thyroid hemiagenesis associated with hyperthyroidism
url http://dx.doi.org/10.1155/2015/829712
work_keys_str_mv AT gunaygurleyik thyroidhemiagenesisassociatedwithhyperthyroidism
AT emingurleyik thyroidhemiagenesisassociatedwithhyperthyroidism