A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review
Ameloblastic fibro-odontoma (AFO) predominantly occurs in the jaw bones of children and young adults. Extraosseous AFO is extremely rare. We describe a peripheral ameloblastic fibro-odontoma in the maxillary gingiva of a 3-year-old girl. The clinical appearance resembled fiery red reactive gingival...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2014/321671 |
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| author | Yi-Chun Lin Hsiu-Ming Hsu Chiang-Shin Liu Kuo Yuan |
| author_facet | Yi-Chun Lin Hsiu-Ming Hsu Chiang-Shin Liu Kuo Yuan |
| author_sort | Yi-Chun Lin |
| collection | DOAJ |
| description | Ameloblastic fibro-odontoma (AFO) predominantly occurs in the jaw bones of children and young adults. Extraosseous AFO is extremely rare. We describe a peripheral ameloblastic fibro-odontoma in the maxillary gingiva of a 3-year-old girl. The clinical appearance resembled fiery red reactive gingival lesions. The histopathological examination of the excised lesion showed small islands and cords of odontogenic epithelium with cellular myxoid stroma in the subepithelial tissue. The mass contained calcified material and an enamel-like deposit. Many small blood vessels appeared in the connective tissue surrounding the odontogenic epithelium. The immunohistochemical assays showed strong reactivity for amelogenin, β-catenin, CD44, and CD31 in the tissue sections. There was no recurrence after the 1-year follow-up. Because this lesion clinically resembles other nonneoplastic lesions and is very rare in gingiva, establishing a correct diagnosis is achieved only based on specific histological characteristics. Conservative excision of the tumor is the treatment of choice. |
| format | Article |
| id | doaj-art-10c9a24074704a8483fa5a23da68027a |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-10c9a24074704a8483fa5a23da68027a2025-02-03T06:06:52ZengWileyCase Reports in Dentistry2090-64472090-64552014-01-01201410.1155/2014/321671321671A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature ReviewYi-Chun Lin0Hsiu-Ming Hsu1Chiang-Shin Liu2Kuo Yuan3Division of Pediatric Dentistry, Department of Stomatology, National Cheng Kung University Hospital, Tainan 704, TaiwanDivision of Pediatric Dentistry, Department of Stomatology, National Cheng Kung University Hospital, Tainan 704, TaiwanDepartment of Pathology, National Cheng Kung University Hospital, Tainan 704, TaiwanInstitute of Oral Medicine, College of Medicine, National Cheng Kung University, Tainan 701, TaiwanAmeloblastic fibro-odontoma (AFO) predominantly occurs in the jaw bones of children and young adults. Extraosseous AFO is extremely rare. We describe a peripheral ameloblastic fibro-odontoma in the maxillary gingiva of a 3-year-old girl. The clinical appearance resembled fiery red reactive gingival lesions. The histopathological examination of the excised lesion showed small islands and cords of odontogenic epithelium with cellular myxoid stroma in the subepithelial tissue. The mass contained calcified material and an enamel-like deposit. Many small blood vessels appeared in the connective tissue surrounding the odontogenic epithelium. The immunohistochemical assays showed strong reactivity for amelogenin, β-catenin, CD44, and CD31 in the tissue sections. There was no recurrence after the 1-year follow-up. Because this lesion clinically resembles other nonneoplastic lesions and is very rare in gingiva, establishing a correct diagnosis is achieved only based on specific histological characteristics. Conservative excision of the tumor is the treatment of choice.http://dx.doi.org/10.1155/2014/321671 |
| spellingShingle | Yi-Chun Lin Hsiu-Ming Hsu Chiang-Shin Liu Kuo Yuan A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review Case Reports in Dentistry |
| title | A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review |
| title_full | A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review |
| title_fullStr | A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review |
| title_full_unstemmed | A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review |
| title_short | A Peripheral Ameloblastic Fibro-Odontoma in a 3-Year-Old Girl: Case Report, Immunohistochemical Analysis, and Literature Review |
| title_sort | peripheral ameloblastic fibro odontoma in a 3 year old girl case report immunohistochemical analysis and literature review |
| url | http://dx.doi.org/10.1155/2014/321671 |
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