The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response
This review provides an overview on components of the sphingolipid superfamily, on their localization and metabolism. Information about the sphingolipid biological activity in cell physiopathology is given. Recent studies highlight the role of sphingolipids in inflammatory process. We summarize the...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2018/5378284 |
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| _version_ | 1832561199053537280 |
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| author | Sabine Grösch Alice V. Alessenko Elisabetta Albi |
| author_facet | Sabine Grösch Alice V. Alessenko Elisabetta Albi |
| author_sort | Sabine Grösch |
| collection | DOAJ |
| description | This review provides an overview on components of the sphingolipid superfamily, on their localization and metabolism. Information about the sphingolipid biological activity in cell physiopathology is given. Recent studies highlight the role of sphingolipids in inflammatory process. We summarize the emerging data that support the different roles of the sphingolipid members in specific phases of inflammation: (1) migration of immune cells, (2) recognition of exogenous agents, and (3) activation/differentiation of immune cells. |
| format | Article |
| id | doaj-art-10bfbb06316f4fef880959d3320a48b3 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-10bfbb06316f4fef880959d3320a48b32025-02-03T01:25:38ZengWileyMediators of Inflammation0962-93511466-18612018-01-01201810.1155/2018/53782845378284The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory ResponseSabine Grösch0Alice V. Alessenko1Elisabetta Albi2University Hospital Frankfurt, Instiute of Clinical Pharmacology, Frankfurt/Main, GermanyEmanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, RussiaDepartment of Pharmaceutical Science, University of Perugia, Perugia, ItalyThis review provides an overview on components of the sphingolipid superfamily, on their localization and metabolism. Information about the sphingolipid biological activity in cell physiopathology is given. Recent studies highlight the role of sphingolipids in inflammatory process. We summarize the emerging data that support the different roles of the sphingolipid members in specific phases of inflammation: (1) migration of immune cells, (2) recognition of exogenous agents, and (3) activation/differentiation of immune cells.http://dx.doi.org/10.1155/2018/5378284 |
| spellingShingle | Sabine Grösch Alice V. Alessenko Elisabetta Albi The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response Mediators of Inflammation |
| title | The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response |
| title_full | The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response |
| title_fullStr | The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response |
| title_full_unstemmed | The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response |
| title_short | The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response |
| title_sort | many facets of sphingolipids in the specific phases of acute inflammatory response |
| url | http://dx.doi.org/10.1155/2018/5378284 |
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