Influences of age and sex on the diagnostic accuracy of human epididymis secretory protein 4 for malignant pleural effusion

Influences of age and sex on the diagnostic accuracy of human epididymis secretory protein 4 for malignant pleural effusion

Abstract Previous studies have suggested that the presence of human epididymal protein 4 (HE4) in pleural fluid can be used to diagnose malignant pleural effusion (MPE) with moderate accuracy. However, the factors that affect the diagnostic accuracy of HE4 remain unknown. This study aimed to examine...

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Bibliographic Details
Main Authors: Qian Yang, Yan Niu, Qianghua Zhou, Dan-Ni Yang, Hong-Zhe Zhu, Cheng Yan, Su-Na Cha, Ting-Wang Jiang, Li Yan, Wen-Qi Zheng, Jian-Xun Wen, Zhi-De Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Human epididymal protein 4
Malignant pleural effusion
Age
Sex
Diagnostic test accuracy
Online Access:https://doi.org/10.1038/s41598-025-86929-5
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