Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip Arthroplasty

Introduction. Total hip arthroplasty (THA) infections with severe bone loss pose significant reconstructive challenges. We present our experience with two-stage hip reimplantation using an intramedullary, antibiotic-impregnated nail. Methods. Three patients with infected THA with severe proximal fem...

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Main Authors: Atul F. Kamath, Okechukwu Anakwenze, Gwo-Chin Lee, Charles L. Nelson
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Advances in Orthopedics
Online Access:http://dx.doi.org/10.4061/2011/398954
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author Atul F. Kamath
Okechukwu Anakwenze
Gwo-Chin Lee
Charles L. Nelson
author_facet Atul F. Kamath
Okechukwu Anakwenze
Gwo-Chin Lee
Charles L. Nelson
author_sort Atul F. Kamath
collection DOAJ
description Introduction. Total hip arthroplasty (THA) infections with severe bone loss pose significant reconstructive challenges. We present our experience with two-stage hip reimplantation using an intramedullary, antibiotic-impregnated nail. Methods. Three patients with infected THA with severe proximal femoral bone loss (Mallory type IIIB or greater) were treated using a custom antibiotic spacer. Clinical outcomes and any complications were recorded. Average followup was 49 months from final reimplantation. Results. Mean age at spacer placement (stage 1) was 53 years. The mean Harris Hip Score at final followup was 80. Two patients had asymptomatic heterotopic ossification, and one patient had a 2 cm leg-length discrepancy. Conclusions. A custom intramedullary nail antibiotic spacer is a reliable option in the staged management of the infected THA with severe proximal femoral bone loss. Benefits of this technique include limb salvage with maintenance of leg length, soft tissue tension, and functional status.
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institution Kabale University
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spelling doaj-art-1099f84a8a7446f3abd9af4d3d3b139f2025-02-03T06:12:15ZengWileyAdvances in Orthopedics2090-34722011-01-01201110.4061/2011/398954398954Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip ArthroplastyAtul F. Kamath0Okechukwu Anakwenze1Gwo-Chin Lee2Charles L. Nelson3Department of Orthopaedic Surgery, University of Pennsylvania, 3400 Spruce Street, 2 Silverstein, Philadelphia, PA 19104, USADepartment of Orthopaedic Surgery, University of Pennsylvania, 3400 Spruce Street, 2 Silverstein, Philadelphia, PA 19104, USADepartment of Orthopaedic Surgery, Penn Presbyterian Medical Center, Cupp 1, 39th and Market Streets, Philadelphia, PA 19104, USADepartment of Orthopaedic Surgery, Geisinger Medical Center, Danville, PA 17822, USAIntroduction. Total hip arthroplasty (THA) infections with severe bone loss pose significant reconstructive challenges. We present our experience with two-stage hip reimplantation using an intramedullary, antibiotic-impregnated nail. Methods. Three patients with infected THA with severe proximal femoral bone loss (Mallory type IIIB or greater) were treated using a custom antibiotic spacer. Clinical outcomes and any complications were recorded. Average followup was 49 months from final reimplantation. Results. Mean age at spacer placement (stage 1) was 53 years. The mean Harris Hip Score at final followup was 80. Two patients had asymptomatic heterotopic ossification, and one patient had a 2 cm leg-length discrepancy. Conclusions. A custom intramedullary nail antibiotic spacer is a reliable option in the staged management of the infected THA with severe proximal femoral bone loss. Benefits of this technique include limb salvage with maintenance of leg length, soft tissue tension, and functional status.http://dx.doi.org/10.4061/2011/398954
spellingShingle Atul F. Kamath
Okechukwu Anakwenze
Gwo-Chin Lee
Charles L. Nelson
Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip Arthroplasty
Advances in Orthopedics
title Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip Arthroplasty
title_full Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip Arthroplasty
title_fullStr Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip Arthroplasty
title_full_unstemmed Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip Arthroplasty
title_short Staged Custom, Intramedullary Antibiotic Spacers for Severe Segmental Bone Loss in Infected Total Hip Arthroplasty
title_sort staged custom intramedullary antibiotic spacers for severe segmental bone loss in infected total hip arthroplasty
url http://dx.doi.org/10.4061/2011/398954
work_keys_str_mv AT atulfkamath stagedcustomintramedullaryantibioticspacersforseveresegmentalbonelossininfectedtotalhiparthroplasty
AT okechukwuanakwenze stagedcustomintramedullaryantibioticspacersforseveresegmentalbonelossininfectedtotalhiparthroplasty
AT gwochinlee stagedcustomintramedullaryantibioticspacersforseveresegmentalbonelossininfectedtotalhiparthroplasty
AT charleslnelson stagedcustomintramedullaryantibioticspacersforseveresegmentalbonelossininfectedtotalhiparthroplasty