IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution
Little is known about the mechanisms that generate epileptic spasms following perinatal brain injury. Recent studies have implicated reduced levels of Insulin-like Growth Factor 1 (IGF-1) in these patients’ brains. Other studies have reported low levels of the inhibitory neurotransmitter, GABA. In t...
Saved in:
Main Authors: | Carlos J. Ballester-Rosado, John T. Le, Trang T. Lam, Anne E. Anderson, James D. Frost, Jr., John W. Swann |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
|
Series: | Neurotherapeutics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878747924001648 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21
by: Henry Chen, et al.
Published: (2025-02-01) -
Integrated analysis of proteomics and metabolomics in infantile epileptic spasms syndrome
by: Jun Chen, et al.
Published: (2025-02-01) -
The significance of focal pattern in hypsarrhythmia
by: Anna Wiedemann, et al.
Published: (2025-03-01) -
Supralinear dendritic integration in murine dendrite-targeting interneurons
by: Simonas Griesius, et al.
Published: (2025-01-01) -
Interneuronal modulations as a functional switch for cortical computations: mechanisms and implication for disease
by: Yann Zerlaut, et al.
Published: (2025-01-01)