The vagus nerve-dependent lung-brain axis mediates brain demyelination following acute lung injury

The vagus nerve-dependent lung-brain axis mediates brain demyelination following acute lung injury

Patients with acute lung injury (ALI) often experience psychiatric and neurological symptoms; however, the precise underlying mechanisms remain unclear. Given that white matter loss (demyelination) contributes to these symptoms, we investigated whether lipopolysaccharide (LPS)-induced ALI leads to b...

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Bibliographic Details
Main Authors: Dan Xu, Mingming Zhao, Guilin Liu, Tingting Zhu, Yi Cai, Rumi Murayama, Yong Yue, Kenji Hashimoto
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Cervical vagus nerve
Demyelination
Lung-brain axis
Subdiaphragmatic vagus nerve
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354625000249
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