Production, Passaging Stability, and Histological Analysis of Madin–Darby Canine Kidney Cells Cultured in a Low-Serum Medium

Production, Passaging Stability, and Histological Analysis of Madin–Darby Canine Kidney Cells Cultured in a Low-Serum Medium

Madin–Darby canine kidney (MDCK) cells are commonly used to produce cell-based influenza vaccines. However, the role of the low-serum medium on the proliferation of MDCK cells and the propagation of the influenza virus has not been well studied. In the present study, we used 5 of 15 culture methods...

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Bibliographic Details
Main Authors: Ming Cai, Yang Le, Zheng Gong, Tianbao Dong, Bo Liu, Minne Su, Xuedan Li, Feixia Peng, Qingda Li, Xuanxuan Nian, Hao Yu, Zheng Wu, Zhegang Zhang, Jiayou Zhang
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Vaccines
Subjects:
MDCK cells
low-serum medium
RNA sequencing
proteomics
flu vaccine
Online Access:https://www.mdpi.com/2076-393X/12/9/991
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