Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature

Angioedema related to a deficiency in the C1-inhibitor protein is characterized by its lack of response to therapies including antihistamine, steroids, and epinephrine. In the case of laryngeal edema, mortality rate is approximately 30 percent. The first case of the acquired form of angioedema relat...

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Main Authors: Bassel Hallak, Propser Konu, Florian Lang, Christian Simon, Philippe Monnier
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2012/405824
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author Bassel Hallak
Propser Konu
Florian Lang
Christian Simon
Philippe Monnier
author_facet Bassel Hallak
Propser Konu
Florian Lang
Christian Simon
Philippe Monnier
author_sort Bassel Hallak
collection DOAJ
description Angioedema related to a deficiency in the C1-inhibitor protein is characterized by its lack of response to therapies including antihistamine, steroids, and epinephrine. In the case of laryngeal edema, mortality rate is approximately 30 percent. The first case of the acquired form of angioedema related to a deficiency in C1-inhibitor was published in 1972. In our paper, we present a case of an acquired form of angioedema of the oropharyngeal region secondary to the simultaneous occurrence of two causative factors: neutralization of C1-inhibitor by an autoantibody and the use of an angiotensin convertin enzyme inhibitor.
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institution Kabale University
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publishDate 2012-01-01
publisher Wiley
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series Case Reports in Otolaryngology
spelling doaj-art-105631ecd7414cd6beec75154d349ade2025-02-03T01:02:35ZengWileyCase Reports in Otolaryngology2090-67652090-67732012-01-01201210.1155/2012/405824405824Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the LiteratureBassel Hallak0Propser Konu1Florian Lang2Christian Simon3Philippe Monnier4Department of Otorhinolaryngology, University Hospital CHUV, Rue du Bugnon 46, 1011 Lausanne, SwitzerlandDepartment of Otorhinolaryngology, Cantonal Hospital Fribourg, Fribourg, SwitzerlandDepartment of Otorhinolaryngology, Cantonal Hospital Fribourg, Fribourg, SwitzerlandDepartment of Otorhinolaryngology, University Hospital CHUV, Rue du Bugnon 46, 1011 Lausanne, SwitzerlandDepartment of Otorhinolaryngology, University Hospital CHUV, Rue du Bugnon 46, 1011 Lausanne, SwitzerlandAngioedema related to a deficiency in the C1-inhibitor protein is characterized by its lack of response to therapies including antihistamine, steroids, and epinephrine. In the case of laryngeal edema, mortality rate is approximately 30 percent. The first case of the acquired form of angioedema related to a deficiency in C1-inhibitor was published in 1972. In our paper, we present a case of an acquired form of angioedema of the oropharyngeal region secondary to the simultaneous occurrence of two causative factors: neutralization of C1-inhibitor by an autoantibody and the use of an angiotensin convertin enzyme inhibitor.http://dx.doi.org/10.1155/2012/405824
spellingShingle Bassel Hallak
Propser Konu
Florian Lang
Christian Simon
Philippe Monnier
Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature
Case Reports in Otolaryngology
title Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature
title_full Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature
title_fullStr Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature
title_full_unstemmed Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature
title_short Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature
title_sort acquired form of angioedema of the head and neck related to a deficiency in c1 inhibitor a case report with a review of the literature
url http://dx.doi.org/10.1155/2012/405824
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