TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch

TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch

Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation of H4 receptor on the dorsal root ganglion (DRG) neurons is still unknown. By using cell culture and calcium imaging, we studied the underlyi...

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Bibliographic Details
Main Authors: Tunyu Jian, Niuniu Yang, Yan Yang, Chan Zhu, Xiaolin Yuan, Guang Yu, Changming Wang, Zhongli Wang, Hao Shi, Min Tang, Qian He, Lei Lan, Guanyi Wu, Zongxiang Tang
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2016/1682972
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