Myelotoxic effects of cholaramphenicol and its metabolites
Chloramphenicol has a broad spectrum of activity against both gram negative and gram positive bacteria, richetsia, and psittacozis-lymphogranuloma group. The most important unwanted eflect of chloramphenicol is depression of the bone-marrow resulting in pancytopenia- an effect which may occur even w...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=676 |
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| author | Ahmet Levent Baş |
| author_facet | Ahmet Levent Baş |
| author_sort | Ahmet Levent Baş |
| collection | DOAJ |
| description | Chloramphenicol has a broad spectrum of activity against both gram negative and gram positive bacteria, richetsia, and psittacozis-lymphogranuloma group. The most important unwanted eflect of chloramphenicol is depression of the bone-marrow resulting in pancytopenia- an effect which may occur even with very low doses in some indivudiats.Within the Turkey the drug is approved for use only in non-food producing animals: it is illegal to use the drug in food animals. Prohibition of chloramphenicol for use in food animals is based in the tendency of chloramphenicol or its metabolites to produce aplastic anemia in certain susceptibie people. In this review, the myelotoxic effects of chloramphenicol and its metabolites are summarized. |
| format | Article |
| id | doaj-art-103ae9da29b049de81feed826bbcd50a |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-103ae9da29b049de81feed826bbcd50a2025-02-03T11:31:17ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531119597676Myelotoxic effects of cholaramphenicol and its metabolitesAhmet Levent BaşChloramphenicol has a broad spectrum of activity against both gram negative and gram positive bacteria, richetsia, and psittacozis-lymphogranuloma group. The most important unwanted eflect of chloramphenicol is depression of the bone-marrow resulting in pancytopenia- an effect which may occur even with very low doses in some indivudiats.Within the Turkey the drug is approved for use only in non-food producing animals: it is illegal to use the drug in food animals. Prohibition of chloramphenicol for use in food animals is based in the tendency of chloramphenicol or its metabolites to produce aplastic anemia in certain susceptibie people. In this review, the myelotoxic effects of chloramphenicol and its metabolites are summarized.http://eurasianjvetsci.org/pdf.php3?id=676chloramphenicolchloramphenicol metabolitesmyelotoxic effect |
| spellingShingle | Ahmet Levent Baş Myelotoxic effects of cholaramphenicol and its metabolites Eurasian Journal of Veterinary Sciences chloramphenicol chloramphenicol metabolites myelotoxic effect |
| title | Myelotoxic effects of cholaramphenicol and its metabolites |
| title_full | Myelotoxic effects of cholaramphenicol and its metabolites |
| title_fullStr | Myelotoxic effects of cholaramphenicol and its metabolites |
| title_full_unstemmed | Myelotoxic effects of cholaramphenicol and its metabolites |
| title_short | Myelotoxic effects of cholaramphenicol and its metabolites |
| title_sort | myelotoxic effects of cholaramphenicol and its metabolites |
| topic | chloramphenicol chloramphenicol metabolites myelotoxic effect |
| url | http://eurasianjvetsci.org/pdf.php3?id=676 |
| work_keys_str_mv | AT ahmetleventbas myelotoxiceffectsofcholaramphenicolanditsmetabolites |