Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal Failure
Purpose. To investigate changes in eye coats, axial length, and ocular perfusion pressure (OPP) in hemodialysis (HD) patients with chronic renal failure (CRF). Methods. We included HD patients who were diagnosed with CRF in our hospital from January to December 2015. Fifty-two patients met the inclu...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2018/3105138 |
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| author | Ling Wang Gang Yin Zhiying Yu Nan Chen Dabo Wang |
| author_facet | Ling Wang Gang Yin Zhiying Yu Nan Chen Dabo Wang |
| author_sort | Ling Wang |
| collection | DOAJ |
| description | Purpose. To investigate changes in eye coats, axial length, and ocular perfusion pressure (OPP) in hemodialysis (HD) patients with chronic renal failure (CRF). Methods. We included HD patients who were diagnosed with CRF in our hospital from January to December 2015. Fifty-two patients met the inclusion criteria; all right eyes were used for observation. Systolic and diastolic blood pressures were recorded to calculate OPP. Approximately 30 minutes before and after HD, we recorded multiple parameters, including lens thickness (LT), axial length of vitreous (VAL), axial length of eye (EAL), ciliary body thickness (CBT), choroidal thickness (CT), and retinal thickness (RT). Results. After HD, OPP significantly decreased (P<0.01, F=7.023) and CBT became significantly thinner (P<0.01, t=3.461). CT was significantly thinner and differed among measurement locations (P<0.01, t=6.240; P<0.01, t=6.169; P<0.01, t=3.405, respectively, fovea, nasal, and temporal side 1500 μm beside the fovea). Further, RT thickened and differed among measurement locations (P<0.05, t=−2.265; P<0.05, t=−2.624; P<0.05, t=−2.220, respectively, fovea, nasal, and temporal side 1500 μm beside fovea), whereas LT, VAL, and EAL significantly increased after HD (P<0.05, t=−2.076; P<0.01, t=−3.817; P<0.01, t=−4.010). Conclusions. HD impacts the thickness of the eye coats and VAL, particularly affecting CBT, CT, and RT. OPP transiently decreases during HD, which may contribute to an ischemic state. |
| format | Article |
| id | doaj-art-1024b26ba2b7495cb4950dfbd85eb1ac |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-1024b26ba2b7495cb4950dfbd85eb1ac2025-02-03T05:58:40ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/31051383105138Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal FailureLing Wang0Gang Yin1Zhiying Yu2Nan Chen3Dabo Wang4Department of Ophthalmology, Affiliated Hospital of Qingdao University, Qingdao 266003, ChinaQingdao Central Hospital, Qingdao 266042, ChinaDepartment of Ophthalmology, Affiliated Hospital of Qingdao University, Qingdao 266003, ChinaDepartment of Ophthalmology, Affiliated Hospital of Qingdao University, Qingdao 266003, ChinaDepartment of Ophthalmology, Affiliated Hospital of Qingdao University, Qingdao 266003, ChinaPurpose. To investigate changes in eye coats, axial length, and ocular perfusion pressure (OPP) in hemodialysis (HD) patients with chronic renal failure (CRF). Methods. We included HD patients who were diagnosed with CRF in our hospital from January to December 2015. Fifty-two patients met the inclusion criteria; all right eyes were used for observation. Systolic and diastolic blood pressures were recorded to calculate OPP. Approximately 30 minutes before and after HD, we recorded multiple parameters, including lens thickness (LT), axial length of vitreous (VAL), axial length of eye (EAL), ciliary body thickness (CBT), choroidal thickness (CT), and retinal thickness (RT). Results. After HD, OPP significantly decreased (P<0.01, F=7.023) and CBT became significantly thinner (P<0.01, t=3.461). CT was significantly thinner and differed among measurement locations (P<0.01, t=6.240; P<0.01, t=6.169; P<0.01, t=3.405, respectively, fovea, nasal, and temporal side 1500 μm beside the fovea). Further, RT thickened and differed among measurement locations (P<0.05, t=−2.265; P<0.05, t=−2.624; P<0.05, t=−2.220, respectively, fovea, nasal, and temporal side 1500 μm beside fovea), whereas LT, VAL, and EAL significantly increased after HD (P<0.05, t=−2.076; P<0.01, t=−3.817; P<0.01, t=−4.010). Conclusions. HD impacts the thickness of the eye coats and VAL, particularly affecting CBT, CT, and RT. OPP transiently decreases during HD, which may contribute to an ischemic state.http://dx.doi.org/10.1155/2018/3105138 |
| spellingShingle | Ling Wang Gang Yin Zhiying Yu Nan Chen Dabo Wang Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal Failure Journal of Ophthalmology |
| title | Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal Failure |
| title_full | Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal Failure |
| title_fullStr | Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal Failure |
| title_full_unstemmed | Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal Failure |
| title_short | Effect of Hemodialysis on Eye Coats, Axial Length, and Ocular Perfusion Pressure in Patients with Chronic Renal Failure |
| title_sort | effect of hemodialysis on eye coats axial length and ocular perfusion pressure in patients with chronic renal failure |
| url | http://dx.doi.org/10.1155/2018/3105138 |
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