Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic Patient
Rhabdomyolysis occurring as a complication of hypophosphatemia has been infrequently described. A 58-year-old male with a history of daily alcohol consumption presented with two generalized tonic clonic seizures secondary to hypovolemic hyponatremia. He was volume-resuscitated, and antiepileptic med...
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| Format: | Article |
| Language: | English |
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Wiley
1999-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1999/376034 |
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| author | Deepali Kumar Finlay A McAlister |
| author_facet | Deepali Kumar Finlay A McAlister |
| author_sort | Deepali Kumar |
| collection | DOAJ |
| description | Rhabdomyolysis occurring as a complication of hypophosphatemia has been infrequently described. A 58-year-old male with a history of daily alcohol consumption presented with two generalized tonic clonic seizures secondary to hypovolemic hyponatremia. He was volume-resuscitated, and antiepileptic medication was administered. After three days of hospitalization, the patient developed severe rhabdomyolysis despite the absence of further seizure activity. Serum phosphate levels were depressed. He was treated with intravenous mannitol, alkaline diuresis, and intravenous and oral phosphate supplementation. He recovered uneventfully. Hypophosphatemia can potentially lead to multisystem organ dysfunction including severe rhabdomyolysis. It is, therefore, important to maintain a low threshold for measuring serum phosphate levels in patients admitted to hospital. |
| format | Article |
| id | doaj-art-0ffceb6a74f741ceb7bb7f56a17ec22f |
| institution | OA Journals |
| issn | 0835-7900 |
| language | English |
| publishDate | 1999-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-0ffceb6a74f741ceb7bb7f56a17ec22f2025-08-20T02:02:32ZengWileyCanadian Journal of Gastroenterology0835-79001999-01-0113216516710.1155/1999/376034Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic PatientDeepali Kumar0Finlay A McAlister1The Division of General Internal Medicine, Ottawa Civic Hospital, Ottawa, Ontario, CanadaCentre for Evidence-Based Medicine, Nuffield Department of Medicine, Level 5, John Radcliffe Hospital, Headington, Oxford, UKRhabdomyolysis occurring as a complication of hypophosphatemia has been infrequently described. A 58-year-old male with a history of daily alcohol consumption presented with two generalized tonic clonic seizures secondary to hypovolemic hyponatremia. He was volume-resuscitated, and antiepileptic medication was administered. After three days of hospitalization, the patient developed severe rhabdomyolysis despite the absence of further seizure activity. Serum phosphate levels were depressed. He was treated with intravenous mannitol, alkaline diuresis, and intravenous and oral phosphate supplementation. He recovered uneventfully. Hypophosphatemia can potentially lead to multisystem organ dysfunction including severe rhabdomyolysis. It is, therefore, important to maintain a low threshold for measuring serum phosphate levels in patients admitted to hospital.http://dx.doi.org/10.1155/1999/376034 |
| spellingShingle | Deepali Kumar Finlay A McAlister Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic Patient Canadian Journal of Gastroenterology |
| title | Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic Patient |
| title_full | Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic Patient |
| title_fullStr | Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic Patient |
| title_full_unstemmed | Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic Patient |
| title_short | Rhabdomyolysis Complicating Unrecognized Hypophosphatemia in an Alcoholic Patient |
| title_sort | rhabdomyolysis complicating unrecognized hypophosphatemia in an alcoholic patient |
| url | http://dx.doi.org/10.1155/1999/376034 |
| work_keys_str_mv | AT deepalikumar rhabdomyolysiscomplicatingunrecognizedhypophosphatemiainanalcoholicpatient AT finlayamcalister rhabdomyolysiscomplicatingunrecognizedhypophosphatemiainanalcoholicpatient |