Identifying the germline variation spectrum and predisposition genes in Chinese ovarian cancer using whole exome sequencing

Identifying the germline variation spectrum and predisposition genes in Chinese ovarian cancer using whole exome sequencing

Abstract Background Next-generation sequencing (NGS) allows for the simultaneous sequencing of multiple cancer predisposition genes. We assessed the frequency and spectrum of germline variations in individuals with ovarian cancer (OC), using whole exome sequencing (WES). Methods A total of 92 patien...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaojing Guan, Sheng Liao, Fenglan Zhang, Qianyuan Zhu, Hao Qiu, Lan Qin, Xiao Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Ovarian cancer
Germline variation
Next-generation sequencing
Predisposition genes
Online Access:https://doi.org/10.1186/s12885-025-14302-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items