New Insights on Properties and Spatial Distributions of Skeletal Stem Cells
Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in v...
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Format: | Article |
Language: | English |
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Wiley
2019-01-01
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Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2019/9026729 |
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author | Jun-qi Liu Qi-wen Li Zhen Tan |
author_facet | Jun-qi Liu Qi-wen Li Zhen Tan |
author_sort | Jun-qi Liu |
collection | DOAJ |
description | Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. Identifying and isolating defined SSCs as well as illuminating their spatiotemporal properties contribute to our understating of skeletal biology and pathology. In this review, we revisit skeletal stem cells identified most recently and systematically discuss their origin and distributions. |
format | Article |
id | doaj-art-0fcd3a4a615e41d8bba6eeb063d2aedf |
institution | Kabale University |
issn | 1687-966X 1687-9678 |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | Stem Cells International |
spelling | doaj-art-0fcd3a4a615e41d8bba6eeb063d2aedf2025-02-03T06:06:49ZengWileyStem Cells International1687-966X1687-96782019-01-01201910.1155/2019/90267299026729New Insights on Properties and Spatial Distributions of Skeletal Stem CellsJun-qi Liu0Qi-wen Li1Zhen Tan2State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaDepartment of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaSkeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. Identifying and isolating defined SSCs as well as illuminating their spatiotemporal properties contribute to our understating of skeletal biology and pathology. In this review, we revisit skeletal stem cells identified most recently and systematically discuss their origin and distributions.http://dx.doi.org/10.1155/2019/9026729 |
spellingShingle | Jun-qi Liu Qi-wen Li Zhen Tan New Insights on Properties and Spatial Distributions of Skeletal Stem Cells Stem Cells International |
title | New Insights on Properties and Spatial Distributions of Skeletal Stem Cells |
title_full | New Insights on Properties and Spatial Distributions of Skeletal Stem Cells |
title_fullStr | New Insights on Properties and Spatial Distributions of Skeletal Stem Cells |
title_full_unstemmed | New Insights on Properties and Spatial Distributions of Skeletal Stem Cells |
title_short | New Insights on Properties and Spatial Distributions of Skeletal Stem Cells |
title_sort | new insights on properties and spatial distributions of skeletal stem cells |
url | http://dx.doi.org/10.1155/2019/9026729 |
work_keys_str_mv | AT junqiliu newinsightsonpropertiesandspatialdistributionsofskeletalstemcells AT qiwenli newinsightsonpropertiesandspatialdistributionsofskeletalstemcells AT zhentan newinsightsonpropertiesandspatialdistributionsofskeletalstemcells |