New Insights on Properties and Spatial Distributions of Skeletal Stem Cells

Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in v...

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Main Authors: Jun-qi Liu, Qi-wen Li, Zhen Tan
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2019/9026729
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author Jun-qi Liu
Qi-wen Li
Zhen Tan
author_facet Jun-qi Liu
Qi-wen Li
Zhen Tan
author_sort Jun-qi Liu
collection DOAJ
description Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. Identifying and isolating defined SSCs as well as illuminating their spatiotemporal properties contribute to our understating of skeletal biology and pathology. In this review, we revisit skeletal stem cells identified most recently and systematically discuss their origin and distributions.
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institution Kabale University
issn 1687-966X
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language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Stem Cells International
spelling doaj-art-0fcd3a4a615e41d8bba6eeb063d2aedf2025-02-03T06:06:49ZengWileyStem Cells International1687-966X1687-96782019-01-01201910.1155/2019/90267299026729New Insights on Properties and Spatial Distributions of Skeletal Stem CellsJun-qi Liu0Qi-wen Li1Zhen Tan2State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaDepartment of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaSkeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. Identifying and isolating defined SSCs as well as illuminating their spatiotemporal properties contribute to our understating of skeletal biology and pathology. In this review, we revisit skeletal stem cells identified most recently and systematically discuss their origin and distributions.http://dx.doi.org/10.1155/2019/9026729
spellingShingle Jun-qi Liu
Qi-wen Li
Zhen Tan
New Insights on Properties and Spatial Distributions of Skeletal Stem Cells
Stem Cells International
title New Insights on Properties and Spatial Distributions of Skeletal Stem Cells
title_full New Insights on Properties and Spatial Distributions of Skeletal Stem Cells
title_fullStr New Insights on Properties and Spatial Distributions of Skeletal Stem Cells
title_full_unstemmed New Insights on Properties and Spatial Distributions of Skeletal Stem Cells
title_short New Insights on Properties and Spatial Distributions of Skeletal Stem Cells
title_sort new insights on properties and spatial distributions of skeletal stem cells
url http://dx.doi.org/10.1155/2019/9026729
work_keys_str_mv AT junqiliu newinsightsonpropertiesandspatialdistributionsofskeletalstemcells
AT qiwenli newinsightsonpropertiesandspatialdistributionsofskeletalstemcells
AT zhentan newinsightsonpropertiesandspatialdistributionsofskeletalstemcells