Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage
DNA is a chemically reactive molecule that is subject to many different covalent modifications from sources that are both endogenous and exogenous in origin. The inherent instability of DNA is a major obstacle to genomic maintenance and contributes in varying degrees to cellular dysfunction and dise...
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Main Authors: | Robert L. Eoff, Jeong-Yun Choi, F. Peter Guengerich |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Journal of Nucleic Acids |
Online Access: | http://dx.doi.org/10.4061/2010/830473 |
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