The effect of high dose digoxin on cytokines in healthy dogs

Background: Tumor necrosis factor (TNF)-α and interleukin (IL)-1β are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs fo...

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Main Authors: Haluk Dülger, Mehmet Ramazan Şekeroğlu, Beyhan Eryonucu, Tevfik Noyan, Süleyman Alici
Format: Article
Language:English
Published: Wiley 2002-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/096293502900000122
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author Haluk Dülger
Mehmet Ramazan Şekeroğlu
Beyhan Eryonucu
Tevfik Noyan
Süleyman Alici
author_facet Haluk Dülger
Mehmet Ramazan Şekeroğlu
Beyhan Eryonucu
Tevfik Noyan
Süleyman Alici
author_sort Haluk Dülger
collection DOAJ
description Background: Tumor necrosis factor (TNF)-α and interleukin (IL)-1β are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs for the treatment of heart failure.
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publishDate 2002-01-01
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series Mediators of Inflammation
spelling doaj-art-0f90655334c54c81912393f65747c64e2025-02-03T05:45:36ZengWileyMediators of Inflammation0962-93511466-18612002-01-0111426126310.1080/096293502900000122The effect of high dose digoxin on cytokines in healthy dogsHaluk Dülger0Mehmet Ramazan Şekeroğlu1Beyhan Eryonucu2Tevfik Noyan3Süleyman Alici4Department of Biochemistry, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, TurkeyDepartment of Cardiology, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, TurkeyDepartment of Cardiology, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, TurkeyDepartment of Biochemistry, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, TurkeyDepartment of Internal Medicine, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, TurkeyBackground: Tumor necrosis factor (TNF)-α and interleukin (IL)-1β are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs for the treatment of heart failure.http://dx.doi.org/10.1080/096293502900000122
spellingShingle Haluk Dülger
Mehmet Ramazan Şekeroğlu
Beyhan Eryonucu
Tevfik Noyan
Süleyman Alici
The effect of high dose digoxin on cytokines in healthy dogs
Mediators of Inflammation
title The effect of high dose digoxin on cytokines in healthy dogs
title_full The effect of high dose digoxin on cytokines in healthy dogs
title_fullStr The effect of high dose digoxin on cytokines in healthy dogs
title_full_unstemmed The effect of high dose digoxin on cytokines in healthy dogs
title_short The effect of high dose digoxin on cytokines in healthy dogs
title_sort effect of high dose digoxin on cytokines in healthy dogs
url http://dx.doi.org/10.1080/096293502900000122
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